Rivaroxaban powder

Rivaroxaban powder initially developed by Bayer.,it’s indicated for the prevention of venous thromboembolic events (VTE) in patients who have undergone total hips replacements and total knee replacement surgery; prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE); to reduce risk of recurrent DVT and/or PE. Due to a lack of safety studies, it is not recommended for use in those under 18 years old. Its use is also not recommended in those with severe renal impairment (<30mL/min).

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Product Description

 

Rivaroxaban powder video

 

 


 

I.Rivaroxaban powder basic Characters:

 

Name: Rivaroxaban powder
CAS: 366789-02-8
Molecular Formula: C19H18ClN3O5S
Molecular Weight: 435.88
Melt Point: 228-229°C
Storage Temp: -20°C Freezer
Color: White to yellowish powder

 


 

II. Rivaroxaban Powder usage:

 

1.Name:

Rivaroxaba, Xarelto.

 

2.Rivaroxaban Powder usage:

Rivaroxaban powder is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.

The most serious adverse effect is bleeding, including severe internal bleeding. Rivaroxaban powder is associated with lower rates of serious and fatal bleeding events than warfarin but is associated with higher rates of bleeding in the gastrointestinal tract. There is currently no antidote for Rivaroxaban powder (unlike warfarin, the action of which can be reversed with vitamin K or prothrombin complex concentrate), meaning that serious bleeding may be difficult to manage.

In October 2014, Portola Pharmaceuticals completed Phase I and II clinical trials for andexanet alfa as an antidote for Factor Xa inhibitors with few adverse effects, and started Phase III trials. Andexanet alfa was expected to be approved in 2016. As of 2017, the compound has yet to be approved by the U.S. Food and Drug Administration.

As of 2015, post-marketing assessments showed liver toxicity, and further studies are needed to quantify the risk. The drug is contraindicated in people with significant liver disease and end-stage kidney disease, in whom the drug was not trialed.

Rivaroxaban powder has a boxed warning to make clear that people using the drug should not discontinue it before talking with their health care professional, because it can increase the risk of stroke.

In 2015, Rivaroxaban powder accounted for the highest number of reported cases of serious injury among regularly monitored drugs to the FDA’s Adverse Events Reporting System (AERS).

Rivaroxaba initially developed by Bayer.,it’s indicated for the prevention of venous thromboembolic events (VTE) in patients who have undergone total hips replacements and total knee replacement surgery; prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE); to reduce risk of recurrent DVT and/or PE. Due to a lack of safety studies, it is not recommended for use in those under 18 years old. Its use is also not recommended in those with severe renal impairment (<30mL/min).

Rivaroxaban powder is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.

 

3.Warning on Rivaroxaba powder

The most commonly reported side-effects is bleeding, including severe internal bleeding
f you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
heavy menstrual bleeding
bleeding from your gums
frequent nosebleeds
coughing up or vomiting blood or material that looks like coffee grounds
bloody, black, or tarry stools
pink, or brown urine
weakness
tiredness
headache
dizziness or fainting
blurred vision
pain in arm or leg
Rash
hives
itching
difficulty breathing or swallowing
pain or swelling at wound sites

 

4.Further instructions:

Rivaroxaban powder is a recently developed oral anticoagulant and direct Factor Xa inhibitor which is used in the prevention of stroke and venous embolism in patients with chronic atrial fibrillation, as well as treatment and prevention of deep venous thromboses and pulmonary embolism. Rivaroxaban powder has been associated with a low rate of serum enzyme elevations during treatment and with rare instances of clinically apparent liver injury with jaundice.

varoxaban is indicated for the prevention of venous thromboembolic events (VTE) in patients who have undergone total hips replacements and total knee replacement surgery; prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE); to reduce risk of recurrent DVT and/or PE. Due to a lack of safety studies, it is not recommended for use in those under 18 years old. Its use is also not recommended in those with severe renal impairment (<30mL/min).

 

5. Rivaroxaban Raw Powder:

Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order(Within 1kg)can be sent out in 3 workingdays after payment.

 

6. Rivaroxaban Raw Powder Recipes:

To inquiry our Customer Representitive(CSR) for details, for your reference.

 

7. Rivaroxaban Marketing:

To be provided in the coming future.

 


 

III. Rivaroxaban Powder HNMR

 

We are Rivaroxaban powder supplie,Rivaroxaban powder for sale,Raw Apixaban powder (366789-02-8) hplc≥98% | AASraw R&D Reagents

 


 

IV. How to buy Rivaroxaban powder from AASraw?

 

1.To contact us by our email inquiry system,or online skypecustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.

 


 

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