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Bupropion HCL powder/Bupropion hydrochloride powder for sale is the hydrochloride type of Bupropion. Bupropion HCL powder/Bupropion hydrochloride powder is white powder, CAS No. is 31677-93-7. Bupropion hydrochloride powder/Bupropion HCL powder, an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines. It is designated as (±)-1-(3-chorophenyl)-2-[(1,1dimethylethyl)amino]-1-propanone hydrochloride. The molecular weight is 276.2. The molecular formula is C13H18ClNO•HCl. Bupropion hydrochloride powder is white, crystalline, and highly soluble in water. It has a bitter taste and produces the sensation of local anesthesia on the oral mucosa. The structural formula is:
Bupropion powder, CAS No.31677-93-7, is an antidepressant originally approved by the U.S. Food and Drug Administration (FDA) in 1989 for the treatment of depression.
Bupropion HCL powder is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain. Buy Bupropion hydrochloride powder from AASraw.
Bupropion HCL powder tablets are supplied for oral administration as 150 mg丨Bupropion 150mg and 300 mg 丨Bupropion 300mg creamy-white to pale yellow extended-release tablets. Each Bupropion HCL powder tablet contains the labeled amount of Bupropion hydrochloride powder and the inactive ingredients: ethylcellulose, glyceryl behenate, methacrylic acid copolymer dispersion, polyvinyl alcohol, polyethylene glycol, povidone, silicon dioxide, and triethyl citrate. The tablets are printed with edible black ink.
The insoluble shell of the extended-release tablet may remain intact during gastrointestinal transit and is eliminated in the feces.
Bupropion hydrochloride powder/Bupropion HCL powder is marketed under the following names:
How does Bupropion HCL powder work? Bupropion HCL powder is an antidepressant medication that affects chemicals within the brain that nerves use to send messages to each other. These chemical messengers are called neurotransmitters. Many experts believe that depression is caused by an imbalance among the amounts of neurotransmitters that are released. Nerves, in a process referred to as reuptake, may recycle released neurotransmitters. Wellbutrin mechanism of action丨Bupropion hydrochloride powder works by inhibiting the reuptake of dopamine, serotonin, and norepinephrine; an action that results in more dopamine, serotonin, and norepinephrine to transmit messages to other nerves. Bupropion is unique and unlike other antidepressants in that its major effect is on dopamine, an effect that is not shared by the selective serotonin reuptake inhibitors or SSRIs (for example, paroxetine [Paxil], fluoxetine [Prozac], sertraline [Zoloft]) or the tricyclic antidepressants or TCAs (for example, amitriptyline [Elavil, Endep], imipramine [Tofranil], desipramine [Norpramin]).
Bupropion hydrochloride powder is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.
Bupropion may also be used for purposes not listed here.
Bupropion is the generic or chemical name of the drug and Budeprion and Wellbutrin are brand names. Drugs can have both a generic name and a brand name. The FDA released a statement that the brand named medication; Budeprion XL 300 mg is not therapeutically equivalent to the brand named medication Wellbutrin XL 300 mg. This means that these two versions of bupropion XL 300 mg do not work the same when given to patients.
When a suffix or ending is attached to a drug that refers to how often it is taken. Bupropion XL (extended release) is taken once daily; bupropion SR (sustained release) and is taken twice daily; and bupropion 300 mg (immediate release) is taken 3 times daily. The FDA statement pertained only to the XL 300 mg dose.
When brand named medications lose their patents, different manufacturers can make their version or the medication can be marketed under the generic name. Generic and brand named drugs should contain the exact same active drug and have the same dosage, intended use, action, side effects, risks, and safety. The difference between generics and different brands of the same drug is that they may vary in the inactive components. These inactive components include dyes and fillers. The FDA does studies to make sure that all the different brands and generic formulations are the same. The FDA did the studies on the dose of bupropion XL 150 mg and concluded that all the manufacturers were making equivalent medications. The FDA did not study the 300 mg dose but assumed the 300 mg would be just as good. Due to complaints from patients, the FDA finally studied the 300 mg dose and found that the Budeprion and the Wellbutrin version of bupropion XL 300 mg were not the same. There was a difference in the rate to which they were released into the blood stream. There are ongoing studies on the manufacturers of other versions of bupropion XL 300 mg.
Some physicians feel that the differences in the inactive components of a drug do influence the availability of a drug to the target tissue (bioavailability). This difference is not usually felt to be clinically significant.
Talk to your doctor about your use of bupropion to determine whether the formulation you are using is the right one for you.
No. Bupropion hydrochloride powder is not considered a narcotic in any medical or legal sense.
While Bupropion hydrochloride powder can have negative side effects, most people do not get high on Wellbutrin and is not addictive. There are anecdotal reports of people attempting to abuse it, but this mostly causes seizures rather than a euphoric high.
Medical narcotics are drugs which provide pain relief. Typically, “narcotics” drugs are opiate medications, which cause sedative effects and slow brain activity. Different narcotics treat varying levels of pain, from moderate to severe, and also other troubling symptoms like cough or diarrhea. Narcotics can cause drowsiness and even loss of consciousness. They can suppress breathing and heart rate, which is sometimes fatal.Bupropion HCL powder acts differently on the body and is not part of this family of drugs.
Bupropion HCL powder uses:
Read the Medication Guide provided by your pharmacist before you start using bupropion and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. If you have stomach upset, you may take this medication with or after a meal or snack. Taking this medication late in the day may cause trouble sleeping (insomnia). Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.The dosage is based on your medical condition, liver function, and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.Do not stop taking this medication without consulting your doctor. Your dose may need to be gradually decreased.It may take 4 weeks or longer before you get the full benefit of this drug. Tell your doctor if your condition does not improve or if it worsens.
Bupropion HCL powder dosage:
Usual Adult Bupropion HCL powder dosage for Depression:
Immediate release tablets:
Initial dose: 100 mg orally twice a day.
Maintenance dose: The dosage may be increased in 75 to 100 mg/day increments not more often than every 3 days up to the usual maintenance dose of 100 mg orally 3 times a day. The maximum dose is 450 mg/day, given in 4 divided doses; bupropion should be discontinued if there is not an adequate response to this dose. Single doses should not exceed 150 mg.
Sustained release tablets:
Initial dose: 150 mg orally once a day in the morning.
Maintenance dose: After at least 4 days, the dose may be increased to 100 to 150 mg twice a day. If there is not adequate improvement after several weeks, the dose may be increased to a maximum of 200 mg twice a day.
Extended release tablets (Wellbutrin XL):
Initial dose: 150 mg orally once a day in the morning.
Maintenance dose: After at least 4 days, the dose may be increased to 300 mg once a day. If there is not adequate improvement after several weeks, the dose may be increased to a maximum of 450 mg once a day in the morning.
Extended release tablets (Aplenzin):
Initial dose: 174 mg orally once a day in the morning (equivalent to 150 mg Bupropion HCL powder).
Maintenance dose: After at least 4 days, the dose may be increased to 348 mg once a day (equivalent to 300 mg Bupropion HCL powder). If there is not adequate improvement after several weeks, the dose may be increased to a maximum of 522 mg once a day in the morning (equivalent to 450 mg Bupropion HCL powder).
Usual Adult Bupropion HCL powder dosage for Seasonal Affective Disorder:
Initiate treatment for seasonal affective disorder in the autumn prior to onset of symptoms.
Wellbutrin XL (R):
Initial: 150 mg orally once a day in the morning
Titration: If tolerated, after 7 days dose may be increased to maximum dose of 300 mg once a day administered in the morning. Patients who are unable to tolerate this increase in dose should be reduced back to 150 mg orally once a day.
Initial: 174 mg once daily (equivalent to 150 mg bupropion) in the morning
Titration: If tolerated, after 7 days dose may be increased to 348 mg once daily (equivalent to 300 mg bupropion) in the morning through the winter season.
Usual Adult Bupropion HCL powder dosage for Smoking Cessation:
Initial Dose: 150 mg orally once a day.
Maintenance: Based on clinical response, this dosage may be increased to 300 mg/day, given as 150 mg twice a day, no sooner than 3 days after beginning therapy.
Bupropion is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience new or worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication, even if treatment is not for a mental/mood condition.Tell the doctor right away if you notice new or worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.If you are using bupropion to quit smoking and experience any of these symptoms, stop taking it and contact your doctor right away. Also, tell your doctor right away if you have any of these symptoms after stopping treatment with bupropion.
Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart disease, high blood pressure, kidney problems, liver disease, use/abuse of drugs/alcohol, seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumor, eating disorders such as bulimia/anorexia nervosa), personal or family history of glaucoma (angle-closure type).This medication should not be used if you are suddenly stopping regular use of sedatives (including benzodiazepines such as lorazepam), drugs used to treat seizures, or alcohol. Doing so may increase your risk of seizures.This drug may make you dizzy. Alcohol or marijuana can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana. Alcohol can also increase your risk of seizures.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially dizziness and memory loss. Dizziness can increase the risk of falling.During pregnancy, this medication should be used only when clearly needed. Since untreated mental/mood problems (such as depression, seasonal affective disorder, bipolar disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention . An overdose of bupropion can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.
Do not use bupropion if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
You should not take bupropion if you are allergic to it, or if you have:
a seizure disorder;
an eating disorder such as anorexia or bulimia; or
if you have suddenly stopped using alcohol, seizure medication, or a sedative such as Xanax, Valium, Fiorinal, Klonopin, and others.
Do not use an MAO inhibitor within 14 days before or 14 days after you take bupropion. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Do not take this medicine to treat more than one condition at a time. If you take bupropion for depression, do not also take this medicine to quit smoking.
Bupropion may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.
To make sure this medicine is safe for you, tell your doctor if you have:
a history of head injury, seizures, or brain or spinal cord tumor;
heart disease, high blood pressure, history of heart attack;
kidney or liver disease (especially cirrhosis);
bipolar disorder or other mental illness; or
if you drink alcohol.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using bupropion. Your family or other caregivers should also be alert to changes in your mood or symptoms.
FDA pregnancy category C. It is not known whether bupropion will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
See also: Pregnancy and breastfeeding warnings (in more detail)
Bupropion can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
The most common side effects of bupropion丨Bupropion side effects include:
Ringing in the ears (tinnitus)
In some people, the agitation or insomnia is most marked shortly after starting therapy.
Urinary tract infections
More serious side effects of Bupropion丨Bupropion side effects include:
High blood pressure (hypertension)
Unusual thoughts or behaviors (hallucinations, paranoia, feeling confused
While depressed mood and lack of interest in activities may need up to 4-6 weeks to improve, disturbances in sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working.
According to the prescribing information for the medication, you may experience changes in body weight when you take Bupropion/Wellbutrin. But the change might be weight loss or weight gain.
In clinical trials lasting up to six months for Wellbutrin XL (extended release oral tablets), about 3 percent of study participants gained more than five pounds while taking 300 mg daily. Two percent gained more than five pounds while taking 400 mg daily and 4 percent gained weight taking the placebo.
With regards to weight loss, 14 percent lost more than five pounds while taking 300 mg daily, while 19 percent lost more than five pounds while taking 400 mg daily. Six percent of study participants lost more than five pounds while taking a placebo.
You may experience weight loss as a side effect of the medication for reasons that are not directly related to the drug. For example, you should not drink alcohol while taking Wellbutrin. If you currently drink on a regular basis, the calorie reduction that happens when you stop consuming alcohol may result in weight loss.
In addition, if you eat to manage depression, you may find that getting some relief from depressive symptoms may help you to eat only when you are hungry and not in response to your feelings.
Bupropion is a prescription medication used to treat depression, prevents seasonal depression, and to quit smoking, depending on the form. Bupropion belongs to a group of drugs called antidepressants, which work by affecting certain natural chemicals in the brain. It is not known how bupropion helps patients quit smoking.
This medication comes in immediate release tablets, sustained-release tablets, and extended-release tablets. The immediate release tablets are usually taken 3 or 4 times daily. The sustained-release tablet is usually taken twice daily. The extended-release tablet is usually taken once daily.
Common side effects of bupropion include nervousness, constipation, trouble sleeping, headache, and nausea.
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