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GW 501516/Cardarine Dosages and Cycling

 

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1.GW 501516/Cardarine Basic information 2.What is Cardarine Used for?
 3.Cardarine: The Cure for Obesity?  4.Effects on Muscle Fibers
5.GW 501516/Cardarine Dosages and Cycling 6.Health Benefits of Cardarine/GW501516
7.Potential Risks/Side Effects 8.Cardarine/GW501516 Recipes
9.Cardarine/GW501516 Raw Powder Basic Characters: 10.How to buy GW501516/Cardarine raw powder from AASraw?

 


 

1.GW 501516/Cardarine Basic informationaasraw

 

Cardarine (GW-501516) is drug that binds to the PPAR receptor. It was first created by Glaxo Smith Kline and Ligand Pharmaceuticals in 1992. It was discovered that Cardarine, when binding to the PPAR receptor, recruits what is called the coactivator PGC-1αenzyme, which then increases the expression of genes involved in the expenditure of energy. Rats treated with Cardarine were shown to have increased fatty acid metabolism and increased protection against obesity from eating a bad diet, as well as an increased protection from type-2 diabetes. In another study on Rhesus monkeys, cardarine was shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol). Reasons for this effect appeared to be caused by an increased expression of the cholesterol transporter ABCA1. In other words, cardarine activates the same genetic pathways that are involved in exercise. In addition, cardarine was studied for use in treating cardio disease before its development was halted in 2007.

 


 

2.What is Cardarine Used for?aasraw

 

Cardarine is great for pretty much everything! Incredible endurance benefits from it are probably the most prominent reason to use this product. Not only has it proven to increase endurance in scientific studies, but when you use it for yourself you’d see that the results are nothing short of amazing! If you’re a cardio junkie or just like getting lean, it increase your run times. Your weight lifting sessions will be extended further, you’ll feel energized longer and ultimately get a lot more work done before you walk out of the gym every day.

 

Of course, fat loss is at the top of the list of reasons why many people love Cardarine so much. Striations and veins get more noticeable and your journey to fat loss becomes a lot easier, without the catabolic effects that most fat burners and drugs can have while trimming down.  Fat loss from cardarine is a result of increased glucose uptake in skeletal muscle. Essentially, you’re making better use of the nutrients you consume every day and decreasing the amount of carbohydrates or fat stored as adipose tissue. As a result, cardarine is not only fat burning and anti-catabolic, but it’s also a little bit anabolic as well.

 

How to use cardarine powder? Cardarine can be stacked with pretty much anything, and it will enhance the results of the cycle. For anabolic-androgenic steroid users who like the drug trenbolone, cardarine is fantastic at combating the negative side effects of “tren” and even enhancing the positive effects.

 

It is better to Post cycle therapy(PCT) when taking steroids (1)

 


 

3.Cardarine: The Cure for Obesity?aasraw

 

THE PRIMARY ROLE is GW’s ability to rid the body of unwanted fatty tissue and it has become almost LEGENDARY. The chemical compounds in this particular PPAR agonist functions in differentiation of adipocytes.

 

Much like growth hormone, sarms powders like GW 501516 generates proinflammatory markers in adipose tissue and decreasing the activity of genes involved in lipogenesis. This means that the body is able to block fatty acid chains from forming and being stored as fat.

 

A study from Scientific Reports published in 2015 stated

 

‘GW501516 acts on PPAR beta cells that exclusively use body fat as energy in the same way the body would when going through ‘starvation mode’.

 

The study is quoted stating: ‘physiological and pathophysiological functions of PPAR and generated novel strategies to treat metabolic diseases’.

 

The activation of these particular genes in the body have been seen to burn body fat at such an alarming rate that it is being coined ‘the cure to obesity’.

 

There were absolutely no adverse side effects detected in the last 20 years of study and it was extremely rare to see muscle wasting at any point during the research.

 


 

4.Effects on Muscle Fibersaasraw

 

The 2015 study by Wei Chen, PhD and his colleges has also found that dramatic increases in the PPAR gene in slow twitch muscle fibers increases oxygen usage and greatly increases endurance. The enhanced endurance was seen in lab mice with a normal oxygen supply and those with oxygen restrictions which provided significant evidence that GW501516 targets and enhances skeletal muscle endurance and recovery time to a supraphysiological level.

 

A study titled ‘A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice’ stated that BCAA were spared during trials of intense exercise which allowed the mice to have a greater rate of recovery in muscle tissue and neurotransmitters.

 

These rats had even lost weight while maintaining a high fat diet, suggesting it could potentially prevent obesity and help manage weight regardless of eatings habits.

 

GW 501516Cardarine Dosages and Cycling AASraw powder suppliers

 


 

5.GW 501516/Cardarine Dosages and Cyclingaasraw

 

The high-end optimal dose is 20mg per day to reap the absolute maximum benefit that Cardarine has to offer. However, I have still seen very decent results and effects from doses as low as 10mg.

 

It is advised that you start at 10mg and assess how you feel, and if you feel you need more of a boost, bump it to 15-20mg per day.

 

The half-life is 24 hours so your dosing time each day is largely irrelevant, although, some users seem to find that dosing it 30-60 minutes pre-workout gives a more notable boost.

 

As long as you get your dose in each day is ultimately what takes a greater priority, but if you choose to dose it pre-workout is up to you based on your personal preference.

 

A cycle should last anywhere from 8-16 weeks. After that point (16 weeks), you will definitely start noticing diminished returns, and you will need to cycle off and take a month off before starting up another Cardarine cycle.

 

Although Cardarine isn’t suppressive whatsoever, or pose any negative side effects that are known, it is recommended to cycle it simply to avoid diminished returns.

 

How to use cardarine powder? Can Men And Women Use Cardarine?

 

Yes, either gender can use it.

 

It isn’t a SARM powder; it is 100% non-suppressive, and poses 0 known negative side effects.

 

The dosing for a woman should be the same as dosing for a man. Women can expect the exact same benefits a man would get from this compound.

 

GW 501516Cardarine Dosages and Cycling AASraw powder suppliers

 


 

6.Health Benefits of Cardarine/GW501516aasraw

 

1) Cardarine Protects the Brain

 

In animals, GW 501516 protects brain vessels when they are under oxidative stress .

Activation of PPARẟ by GW 501516 could drive the development of nerve cells .

Additionally, it prevents blood vessel dysfunction, especially in brain vessels .

 

2) Cardarine Benefits the Heart

 

Comparing with the others SARMS powders, GW 501516 prevents oxidative damage in the heart.

It decreases the risk and severity of atherosclerosis (plaque buildup in the arteries) through a number of mechanisms. GW 501516 increased levels of nitric oxide, which protects against atherosclerosis.

 

It also reduces lesions and inflammation associated with atherosclerosis in mice.

GW 501516 increases VEGF production from human blood vessel cells, which triggers cell and blood vessel formation .

 

GW 501516 results in an increase of HDL cholesterol and a decrease in triglycerides in animal studies, potentially decreasing the risk of cardiovascular disease in patients.

 

3) Cardarine Increases Metabolism and Prevents Obesity

 

GW 501516 activates PPARẟ, which may increase the breakdown of fatty acids and increase energy expenditure in muscle. This could help treat obesity.

 

PPARẟ activates the expression of a number of genes involved in reducing cholesterol and increasing energy expenditure . This treatment could protect against weight gain due to diet.

 

Also, GW 501516 decreases glucose output by the liver and increases insulin sensitivity in mice. By driving muscle fiber development in mice, GW 501516 creates a resistance to obesity.

 

4) Cardarine Protects the Kidneys

 

In mice, it was shown to inhibit inflammation in kidney cells, and may protect against kidney disease. It does this by lowering MCP-1 expression that is generally increased in such kidney diseases .

 

5) Cardarine Helps the Immune System

 

GW 501516 is associated with the suppression of inflammation .

Activated PPARẟsuppresses inflammation in the liver in animals by inhibiting molecules that contribute to inflammatory responses.

 

GW 501516 can activate PPARẟ which protects specific skin cells from undergoing spontaneous cell death during the wound healing process . It was also shown to accelerate diabetic wound closure.

 

6) Cardarine Protects Against Liver Damageaasraw

 

PPARẟ activation by GW 501516 causes the liver to switch its energy source from glucose to fatty acids, thus reducing blood sugar.

 

In mice, GW 501516 inhibited IL-6, which may help prevent insulin resistance in liver cells . Short-term use can reverse the liver damage that was due to a high fructose diet.

 

Also, it can improve nonalcoholic liver disorder in mice.

 

7) Cardarine Improves Muscle Growth and Stamina

 

Activation of PPARẟ via GW501516 drives the development of muscle fibers in mice. These muscle fibers are associated with increased physical performance. They were able to run almost twice as long as other mice, indicating improved endurance.

 

8) Cardarine May Help Heal Skin Diseases

 

Activation of PPARẟ could improve the inflammation caused by psoriasis (a skin disorder).

 

9) Cardarine May Improve Blood Flow and Wound Healing

 

By activating PPARẟ, Cardarine may increase the synthesis of BH4, which increases nitric oxide production in blood vessels (eNOS).

 

Increasing nitric oxide helps improve blood flow. It also helps during wound healing.

 

10) Cardarine Has Antioxidant and Anti-inflammatory Potential

 

Not like other SARMS powder, Cardarine increases the production of the antioxidant enzymes SOD1 and catalase.

 

It also inhibits the production of inflammatory molecules such as MCP-1, TNF-alpha, IL-6, and NFκB . The anti-inflammatory effects can improve fibrosis caused by inflammation in rats.

 


 

7.Potential Risks/Side Effectsaasraw

 

GW 501516 increases cell death in liver cells and may cause fibrosis in mice with liver disease.

 

In animals, there is a potential risk to placental and fetal development with prolonged are large exposure to GW 501516.

 

In rats, GW 501516 can cause cancer. There are not enough studies done on humans to show the same effect.

 

GSK abandoned further development of the drug in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.

 

Because GW 501516 has a vast amount of influence in a number of places in the body, you should consider its side effects before pursuing it as a treatment.

 

Then, how to use cardarine powder?

 


 

8.Cardarine/GW501516 Recipesaasraw

 

SARMS POWDER RECIPES:

Ostarine (MK-2866)  25mg/ml oral liquid recipe:

15g Ostarine(MK2866) powder

600ml Edible Alcohol

 

Andarine (S-4) 25mg/ml oral liquid recipe:

15g Andarine (S-4) powder

600ml Edible Alcohol

 

Gw-501516 (Cardarine) 10mg/ml oral liquid recipe:

10g  Gw-501516 (Cardarine)  powder

1000ml Edible Alcohol

 

The liquid usually will be stored in glass dropper bottles.

 

GW 501516Cardarine Dosages and Cycling AASraw powder suppliers

 


 

9.Cardarine/GW501516 Raw Powder Basic Characters:aasraw

 

Name: GW501516/Cardarine

Catalog: SARMS powder

CAS: 317318-70-0

Molecular Formula: C21H18F3NO3S2

Molecular Weight:   453.498

Melt Point: 134-136℃

Storage Temp: RT

Solubility  : Water (slightly), DMSO, Ethanol

Color: Light yellow crystal powder

Organoleptic Profile: White to beige fine powder, odorless, bitter taste

As for how to use cardarine powder, please consult the sales representative.

GW 501516Cardarine Dosages and Cycling AASraw powder suppliers

 


 

10.How to buy GW501516/Cardarine raw powder from AASraw?aasraw

 

1.To contact us by our email inquiry system, or online Skype customer service representative(CSR).

2.To provide us your inquired quantity and address.

3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).

4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).

5.Goods received and give comments.

 


 

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