Everything about Fosaprepitant Dimeglumine powder


  1.What is Guggulsterones(guggul)?
  2.Guggulsterones(guggul) name
  3. Guggulsterones(guggul) chemical information
  4.Where does Guggulsterone(guggul) come from?
  5. How does Guggulsterone work?
  6.Guggulsterones(guggul) for weight loss
  7. Guggulsterones(guggul) for bodybuilding
  8.Guggulsterones(guggul) effect on thyroid and hormone
  9. Guggulsterones dosage/guggul dosage
  10.Guggulsterones(guggul) warning
  11. Guggulsterones(guggul) interactions
  12.Is it safe to use Ayurvedic medicine(Guggulsterones)
  13. Guggulsterones(guggul) side effects
  14.Guggulsterones(guggul) reviews



Guggulsterone powder video



I.Raw Guggulsterone powder basic Characters:


Name: Guggulsterone powder
CAS: 95975-55-6
Molecular Formula: C21H28O2
Molecular Weight: 312.45
Melt Point: 170-171.5°C
Storage Temp: 2-8°C
Color: Light yellow powder


1. What is Guggulsterones(guggul)?aasraw


Guggulsterones(guggul), CAS No. 95975-55-6,is made from the sap (gum resin) of the Commiphora mukul tree, which is native to India. This tree has been used in Ayurvedic medicine for centuries, and Ayurvedic texts dating back to 600 BC recommend it for treating atherosclerosis.

Today guggul gum resin is used for arthritis, lowering high cholesterol,hardening of the arteries” (atherosclerosis), acne and other skin diseases, and weight loss.



2. Guggulsterones(guggul) nameaasraw


Devadhupa, Balsamodendrum wightii, Balsamodendrum mukul, Commiphora mukul, Commiphora wightii, Gomme Guggul, Gomme-Résine de Guggul, Guggal, Guggul Gum Resin, Guggul Lipids, Guggulipid, Guggulipide, Guggulu, Guggulu Suddha, Guggulsterone, Guggulstérone, Guggulsterones, Guggulstérones, Guglipid, Gugulipid, Gum Guggal, Gum Guggulu, Indian Bdellium, Indian Bdellium-Tree, Koushika, Mukul Myrrh Tree, Palankasha, Yogaraj Guggul Gum Resin



3. Guggulsterones(guggul) chemical informationaasraw


Guggulsterone(guggul) chemical information
Name Guggulsterone,guggul,Ayurvedic
CAS 95975-55-6
Molecular Formula C21H28O2
Raw Guggulsterone powder (95975-55-6) hplc≥98% | AASraw R&D Reagents
Molecular Weight 312.45
Melt Point 170-171.5°C
Storage Temp 2-8°C
Color Light yellow powder
Manufacturer www.aasraw.com 
Payment term WU,MG,BT,T/T
Package customization


4. Where does Guggulsterone(guggul) come from?aasraw


Guggulsterone(guggul) was first discovered and implemented into herbal medicine hundreds of years ago throughout its native land of India. As a natural herbal remedy, guggul sap from the myrrh tree was originally believed to help improve bile production and secretion, with the intended effect of lowering LDL cholesterol within the bloodstream. Conflicting studies report that some of these claims may be inaccurate, and that guggulsterones may have little to no effect on cholesterol levels, whatever Continued research is warranted, in either case.



Grown in India, Guggul is a tree which exudes a resinous sap out of incisions that are made in its bark. This resin has been used for centuries as part of India’s traditional medicine called Ayurveda. In our modern world of advanced chemistry, this resinous sap is processed and purified, and then standardized for a given amount of its active constituents-Z and E Guggulsterones(guggulsterones dr oz). These two compounds are plant sterols with a high degree of human bioactivity and have been shown in studies to affect many biological processes including thyroid metabolism, cholesterol management, and dermal (skin) function. In each of these areas, Guggulsterones were shown in studies to be highly effective modulators with near drug-like potency.



5. How does Guggulsterone work?aasraw


Guggul (or gugulipid) is a traditional Ayurvedic herb used to support healthy cholesterol levels already within the normal range. In addition, it’s also used for weight management. How does Guggulsterone work?

Guggul contains substances that lower cholesterol and triglycerides. One of these substances also decreases the redness and swelling that occurs in some types of acne.



6. Guggulsterones(guggul) for weight lossaasraw


Guggulsterones are the active component of the Aryuvedic herb Commiphora mukul, also known as gugulipids. Several new studies suggest that guggulsterones are helpful for weight loss.

In an animal experiment rats were fed a high fat diet for 16 weeks. As expected, the rats developed increased serum glucose, cholesterol and triglyceride levels along with increase in insulin resistance significantly, in  comparison to control animals. The rats fed guggulsterones along with the high fat diet demonstrated significantly improved blood sugar and fat burning metabolism.  Furthermore, guggulsterones directly interacted with baby fat cells, inhibiting them from becoming mature fat storing cells. The researchers concluded that
“guggulsterone has both hypoglycemic and hypolipidemic effect which can help to cure type II diabetes.”

Another cell study confirmed the effects of guggulsterone on fat cells1. It was shown that guggulsterones decreased the number of mature fat cells, reduced the storage of fat in mature fat cells.  These results show that guggulsterones are promoters of an active fat burning metabolism, protecting against fat accumulation.



7. Guggulsterones(guggul) for bodybuildingaasraw


Bodybuilding, being a sport of aesthetics, is not only concerned about building solid muscle tissue but also reducing the amount of fat deposits. Guggulsterones bodybuilding,You might weigh 240 pounds and have a tremendous amount of muscular development but if you have two inches of subcutaneous fat all over your body you won’t look all that great. You definitely won’t be aesthetically pleasing and some people might even call you Doughboy. Well, if you’re anything like the Guggul tree you won’t want to be called names so you’ll work hard at looking your best. Fortunately, in the case of fat loss, Guggul understands your dilemma and is right there to help you meet your goals(guggulsterones bodybuilding).


Guggulsterones(guggul) for weight loss and bodybuilding


When the thyroid gland is stimulated, it produces more thyroid hormones such as thyroxin. These thyroid hormones have a profound effect on the rate of metabolism including a direct catabolic effect on adipose tissue. Practically, this means that Guggulsterones will stimulate your thyroid to produce more thyroid hormones which in turn will raise your metabolic rate and burn more fat! Guggulsterones by themselves have been shown to work very well for fat loss but I have found a combination that is nothing short of amazing-Guggulsterones and an ECA stack such as the now discontinued Adipokinetix. We already know that Adipokinetix is an extremely potent fat burner but it does its work outside the realm of the thyroid.

It made sense to me that if one could combine the fat burning effects of the thyroid hormones with that of the adrenergic hormones (e.g. adrenaline) something very dramatic would result. Also, interesting is the fact that ECA type stacks tend to decrease the amount of thyroid hormones circulating in the blood over time. Guggulsterones do a great job of inhibiting this reduction, thus keeping all physiological fat burning systems operating at a maximum level.

The final ways that Guggulsterones can benefit in the fight to burn fat is in ketogenic diets and growth hormone use. Over time, ketogenic diets tend to reduce the thyroid’s effectiveness by reducing the conversion of T4 to the more potent T3. Also, where Guggulsterones were taken daily for 3 months, they produced a progressive reduction in lesions in the majority of the patients. With tetracycline, the percentage reduction in the inflammatory lesions was 65.2% as compared to 68% with the Guggulsterones. As you can see, our friend Guggul is extremely potent at fighting acne(guggulsterones acne)



8. Guggulsterones(guggul) effect on thyroid and hormoneaasraw


Guggulsterones(guggul) is a unique compound that has been studied for its potential fat-burning effects for years.* Unlike many other fat burners, which work to raise the heart-rate or improve the body’s natural metabolism of certain fats and sugars, guggul extract (and its active ingredient, guggulsterones) is said to have an effect on the thyroid and hormone production related to metabolism(guggulsterones thyroid).

What has more people interested in this Guggulsterones(guggul) is its potential as a mechanism for weight loss, acting through the thyroid to create a balance in the hormones triiodothyronine (T3) and thyroxine (T4) which govern metabolism(guggulsterones thyroid). In one commonly-cited study conducted at the Devi Ahilya University in India, researchers observed an increase in T3 concentration in animal subjects that were given an extract of the guggul plant, while T4 levels remained unchanged. This suggests that a human application of this material may produce the same positive results in conjunction with proper diet and exercise, especially in individuals that suffer from thyroid imbalances like hypothyroidism. A human trial that was conducted in 1995 with 58 overweight individuals did seem to confirm these findings, with an average weight loss of 4.95 pounds observed in individuals that were administered the material over the course of 30 days as compared to the control group6.

More importantly, these effects may be achieved without the stimulation of the central nervous system, as guggulsterones strictly act upon the thyroid.* This is especially important for individuals that may be suffering from heart conditions of any kind, or individuals who may be looking for additional aid in losing weight without the undesired jitters and crash that may often accompany the use of many CNS-stimulants.

guggulsterones acne



9. Guggulsterones dosage/guggul dosageaasraw


A standard dose of guggul/guggul dosage (plant extract) is 400-500mg taken thrice daily with meals, totaling 1,200-1,500mg daily (although doses up to 2,000mg have been used before) If using the guggulsterones dosage in isolation, a dose of 25mg taken thrice a day with meals is used.

Sometimes ‘gum guggul’ is used in doses of 2-4.5g a day (total), and while it is not sure if guggul needs to be consumed with meals it still tends to be recommended out of prudency.



10. Guggulsterones(guggul) warningaasraw


-Pregnancy and breast-feeding

Guggul is LIKELY UNSAFE during pregnancy. It seems to encourage menstrual flow and stimulates the uterus, so some researchers worry that it might endanger the pregnancy. Not enough is known about the safety of using guggul during breast-feeding. Do not use guggul if you are pregnant or breast-feeding.


-Bleeding disorders

Guggul can slow blood clotting and might cause bleeding or bruising in people with bleeding disorders.


-Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids

Guggul might act like estrogen in the body. If you have any condition that might be made worse by exposure to estrogen, do not use guggul.

-Underactive or overactive thyroid (hypothyroidism or hyperthyroidism)

Guggul might interfere with treatment for these conditions. If you have a thyroid condition, don’t use guggul without your healthcare provider’s supervision.



Guggul might increase the risk of bleeding during and after surgery. Stop using guggul at least 2 weeks before a scheduled surgery.



11. Guggulsterones(guggul) interactionsaasraw


-Birth control pills (Contraceptive drugs) interacts with GUGGUL

Some birth control pills contain estrogen. Guggul might theoretically increase the side effects of birth control pills. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.


-Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GUGGUL

Some medications are changed and broken down by the liver.Guggul might increase how quickly the liver breaks down some medications. Taking guggul along with some medications that are broken down by the liver can decrease the effectiveness of some medications. Before taking guggul talk to your healthcare provider if you are taking any medications that are changed by the liver.<br/><br/> Some medications changed by the liver include lovastatin (Mevacor), atorvastatin (Lipitor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.


-Propranolol (Inderal) interacts with GUGGUL

Guggul might decrease how much propranolol (Inderal) the body absorbs. Taking guggul along with propranolol (Inderal) might decrease the effectiveness of propranolol (Inderal).

-Tamoxifen (Nolvadex) interacts with GUGGUL

Some types of cancer are affected by hormones in the body. Estrogen-sensitive cancers are cancers that are affected by estrogen levels in the body. (Nolvadex) is used to help treat and prevent these types of cancer. Guggul could theoretically affect estrogen levels in the body. By affecting estrogen in the body, guggul might decrease the effectiveness of tamoxifen (Nolvadex). Do not take guggul if you are taking tamoxifen (Nolvadex).



12. Is it safe to use Ayurvedic medicine(Guggulsterones)aasraw


The ancient practice of Ayurvedic medicine(Guggulsterones)has clearly helped millions of people create healthier lives. However, like any other medical system, Ayurvedic therapies have contraindications and the potential for adverse effects or side effects.

Many Ayurvedic adherents argue that the system’s incredible longevity offers a powerful argument for its success and safety. However, most of the information regarding Ayurveda’s efficacy has been passed from teacher to student. In addition to this “oral history,” the ancient books Charak Samhita and Sushruta Samhita contain observational documentations about the system’s effectiveness.

Although there is not a large body of clinical research on Ayurveda, many of the system’s principles and practices are now recognized and used in conventional medical settings. For example, the Ayurvedic tenant of the psychological and physical impact humans experience during the changing of seasons is borne out in research on SAD (seasonal affective disorder).

There is also medical and layperson acknowledgement of the health benefits of Ayurvedic practices, such as yoga, massage, and meditation. Herbs used in Ayurvedic medicine, such as tumeric, ginger, and neem, are now recognized as beneficial for heart health and as antioxidant-boosters. See the References and Further Reading section below for examples of research studies that are beginning to emerge on the use of specific Ayurvedic herbs.

Western knowledge of Ayurvedic medicine(Guggulsterones)  is still in its infancy, thus skepticism exists. As the use of Ayurvedic medicine grows, and as more practitioners share their knowledge with other healthcare providers, this wariness of Ayurveda may transform into appreciation and knowledge of the system.



13. Guggulsterones(guggul) side effectsaasraw


A yellowish resin extracted from the guggul plant contains substances called guggulsterones and possibly others. Laboratory studies have found that guggulsterones can change the metabolism of cholesterol by the liver. Guggulsterones may also increase the production of thyroid hormones and are commonly included in weight loss supplements for that purpose. Products containing guggul extracts should be taken with caution because of their risk of side effects.


-Interaction with Disease

Those being treated for thyroid disorders, including both hypo- and hyperthyroidism, should consult their doctor before taking guggul extract. People with liver or kidney disease may not metabolize guggul extract normally and should not take it. In general, consult your doctor to determine whether guggul extract is safe for you.

-Interactions with Medicines

Guggul extract should not be taken with warfarin, aspirin, nonsteroidal anti-inflammatory drugs or any other drugs that inhibit blood clotting. Guggul extract may increase the risk of severe or uncontrolled bleeding when taken with these drugs. Guggul extract may interact with synthetic thyroid hormones or other medications used to treat thyroid disorders. Taken together, guggul and thyroid medications can raise the risk of thyroid storm, a potentially life-threatening condition in which very large amounts of thyroid hormones are produced. Guggul extract may greatly reduce the effectiveness of the drugs propranolol or diltiazem.


-Other Possible Side Effects

Little scientific information exists on the potential toxicity of guggul extract. It is unknown whether guggul is safe during pregnancy, but because of effects on thyroid hormones and lipid metabolism it should probably be avoided. Guggul extract may cause headache, nausea, gastrointestinal disturbances and rash. Allergic reactions to guggul extract have been reported.



14. Guggulsterones(guggul) reviewsaasraw


Guggulsterones(guggul) are the bioactive compounds (alkaloids) found in Commiphora Mukul. Guggul has been used in Indian Ayurvedic medicine for more than 2,000 years for a variety of ailments and has more recently come to attention in Western medicine for possible cholesterol-lowering, dermatalogical, anti-inflammatory, anti-arthritic and anti-obesity benefits.




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