BD-AcAc2 (1208313-97-6) - Manufacturer Factory Supplier
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BD-AcAc2 Powder

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BD-AcAc2 is a ketone ester with anti-obesity and anticonvulsant activities. Oral administration of BD-AcAc2 reduces body weight, food intake, and whole animal adiposity in mice fed an isocaloric diet. BD-AcAc2 increases the seizure threshold and blood levels of β-hydroxybutyrate in a rat model of seizures induced by pentylenetetrazole.

Product Description

BD-AcAc2 Powder Basic Characteristics

Product Name BD-AcAc2
CAS number 1208313-97-6
Synonyms Ketone Ester;

R-BHB;

(R)-3-Hydroxybutyl (R)-3-hydroxybutyrate;

(R)-3-Hydroxybutyl(R)-3-hydroxybutyrate ketone ester;

(R)-(R)-3-hydroxybutyl 3-hydroxybutanoate.

Molecular Formula C8H16O4
Formula Weight 176.21
Boiling point 269℃
Appearance Solid powder
Solubility Soluble in DMSO
SMILES Code C[[email protected]](CCOC(C[[email protected]@H](C)O)=O)O
InChi Key AOWPVIWVMWUSBD-RNFRBKRXSA-N
InChi Code InChI=1S/C8H16O4/c1-6(9)3-4-12-8(11)5-7(2)10/h6-7,9-10H,3-5H2,1-2H3/t6-,7-/m1/s1
Storage Condition Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).

 

Reference

[1] D’Agostino DP, et al. Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats. Am J Physiol Regul Integr Comp Physiol. 2013 May 15;304(10):R829-36.

[2] Kashiwaya Y, et al. A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer’s disease. Neurobiol Aging. 2013 Jun;34(6):1530-9.

 

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