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Flumethasone Powder (2135-17-3)

Rating: SKU: 2135-17-3. Category:

AASraw is with synthesis and production ability from gram to mass order of Flumethasone Powder (2135-17-3), under CGMP regulation and trackable quality control system.

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Product Description

 

Flumethasone Powder (2135-17-3) video

 

 


 

Flumethasone Powder (2135-17-3) Specification:

Chemical Structure: Product Name: Flumethasone
Cas No.: 2135-17-3
Molecular Formula: C22H28F2O5
Molecular Weight: 384.51
Standard: In-house
Storage: 2-8°C
Documents(COA & HPLC etc.): Available

 

Flumethasone Powder (2135-17-3) Description:

Flumetasone, also known as RS 2177. It is available in combination with clioquinol, under the trade name Locacorten-Vioform (in some countries Locorten-Vioform), for the treatment of otitis externa and otomycosis.

Flumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. Its mechanism of action is thought to inhibit arachidonic acids role in the biosynthesis of prostaglandins and leukotrienes. Flumethasone is active when it is not bound to the plasma protein transcortin . The drug flumethasone can be used to treat a variety of skin conditions, such as contact dermatitis, bug bites and eczema.

 

Reference:

  • 1: Van Den Hauwe O, Schneider M, Sahin A, Van Peteghem CH, Naegeli H. Immunochemical screening and liquid chromatographic-tandem mass spectrometric confirmation of drug residues in edible tissues of calves injected with a therapeutic dose of the synthetic glucocorticoids dexamethasone and flumethasone. J Agric Food Chem. 2003 Jan 1;51(1):326-30. PubMed PMID: 12502428.
  • 2: Brambilla G, Buiarelli F, Cartoni GP, Coccioli F, Colamonici C, Fagiolo A, Giannini C, Neri B. Determination of flumethasone in calf urine and serum by liquid chromatography-tandem mass spectrometry. J Chromatogr B Biomed Sci Appl. 2001 May 5;755(1-2):265-78. PubMed PMID: 11393713.
  • 3: Sternbauer K, Luthman J, Jacobsson SO. Flumethasone-induced insulin resistance in calves. Zentralbl Veterinarmed A. 1998 Sep;45(6-7):441-3. PubMed PMID: 9793474.