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Coenzyme Q10 powder

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Coenzyme Q10 powder, also called Ubidecarenone, is a 1,4-benzoquinone with a side chain of 10 isoprenoid units. Occurring isomer naturally , all isoprenyl double bonds are in the E- configuration, has an important in electron transport in mitochondrial membranes. Coenzyme Q10 powder works with a role as a human metabolite, a ferroptosis inhibitor and an antioxidant, plays as an endogenous  powerful antioxidant and free radical scavenger, displays neuroprotective activity.

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Product Description

Coenzyme Q10 Powder Basic Characteristics

Product Name COENZYME Q10 powder
CAS Number 303-98-0
Molecular Formula C59H90O4
Formula Weight 863.4
Synonyms Coenzyme Q10;

ubiquinone-10;

ubidecarenone;

Ubiquinone Q10;

COQ 10;

Q 10AA;

Unispheres Q 10;

Appearance Yellow to dark orange powder
Storage and Handling −20°C

 

What Is COENZYME Q10 powder?

Coenzyme Q10 powder, also called Ubidecarenone, is a 1,4-benzoquinone with a side chain of 10 isoprenoid units. Occurring isomer naturally , all isoprenyl double bonds are in the E- configuration, has an important in electron transport in mitochondrial membranes. As studies indicate that Coenzyme Q10 powder can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. Other than that, Coenzyme Q10 powder inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 powder be known to suppress the down regulation of NOS3 (endothelial nitric oxide synthase, eNOS) and up-regulation of NOS2 (inducible nitric oxide synthase, iNOS). As a result of its ability to bind Ca2+, can transport this cation across artificial biomimetic membranes. Coenzyme Q10 powder works with a role as a human metabolite, a ferroptosis inhibitor and an antioxidant, plays as an endogenous  powerful antioxidant and free radical scavenger, displays neuroprotective activity. In an animal model of Huntington’s disease, Coenzyme Q10 powder extends survival and delays disease; this effect is more pronounced when combined with Remacemide hydrochloride (Cat. No. 1622). Ferroptosis inhibitor. At present, Coenzyme Q10 powder is mainly sold as a dietary supplement, it’s featured in many forms including capsules, tablets, skin creams, and combination supplements, widely be used in physiology, pharmacy, cosmetics and health protection.

 

Coenzyme Q10 Powder Applications

Coenzyme Q10 powder is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 powder can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. It ‘s also a free radical scavenger in lipid and mitochondrial membranes. Coenzyme Q10 has antibacterial and antioxidative properties and used to treat heart and blood vessel conditions, such as congestive heart failure (CHF), chest pain (angina), high blood pressure. It is also used for preventing migraine headache, Parkinson disease, and many other conditions. Reduce the oxidative damage that leads to muscle fatigue, skin damage and brain and lung diseases.

In meanwhile, Coenzyme Q10 powder has also been used as an active ingredient in cosmeceuticals and as an inactive ingredient in sunscreen formulations. When applied topically in skincare products Coenzyme Q10 powder demonstrates some ability to reduce oxidative stress in the skin, delay signs of intrinsic skin aging, reverse signs of extrinsic skin aging,assist in fading dyspigmentation,increase stability of certain sunscreen actives, increase the SPF of sunscreens, and afford some infrared protection to sunscreens.

 

How Does Coenzyme Q10 Powder Work

Coenzyme Q10 is an important component of the cells’ mitochondria, plays an important role in the creation of ATP, particularly in the electron transfer chain. Coenzyme Q10 powder work on our body by three aspect as blew:

 

Invigorates cell activity

Coenzyme Q10 powder can helps contributes to maintaining healthy skin cells and make it efficiently as possible.

 

❷ Supports collagen and elastin production

By spurring on cell activity, coenzyme Q10 powder can help to maintain a healthy supply of new collagen and elastin, make your complexion firm and plump. Elastin gives your skin elasticity.

 

❸ Helps fight off free radicals

Free radicals attack elastin and collagen causing them to lose shape. Coenzyme Q10 as an antioxidant can help to shield your skin cells from this oxidative stress and allows toxins to be flushed out more efficiently.

 

What Is The Benefit Of Coenzyme Q10 Powder

Coenzyme Q10 powder offers a wide range of potential benefits including:

 

 Support heart health

Coenzyme Q10 Powder can help maintain normal blood pressure ‘without significant side effects’. If taking medication for high blood pressure (or any other medication), talk to your GP before taking Coenzyme Q10 Powder.

 

♦ Reduce the signs of ageing

As you age, adding Coenzyme Q10 Powder to your skincare routine enables skin cells to repair and regenerate more efficiently. And make a dull and tired complexion can get a radiance boost.

 

♦ Radiance

As you age, adding CoQ10 to your skincare routine enables skin cells to repair and regenerate more efficiently. As a result, a dull and tired complexion can get a radiance boost.

 

♦ Firming

Coenzyme Q10 Powder can reduce the appearance of fine lines and wrinkles and appear healthy production of new collagen.

 

♦ More even skin tone

Coenzyme Q10 powder can inhibit the production of tyrosinase – a substance that facilitates the production of melanin.If excess production of melanin can cause dark spots and patches of hyperpigmentation to form. So Coenzyme Q10 powder skincare can limit the worsening of these changes in skin tone.

 

♦ Skin-soothing

Coenzyme Q10 Powder as an antioxidant that helps to shield your skin from irritants and damage from external factors.

 

♦ Coenzyme Q10 powder and Alzheimer’s disease

Some studies indicate a link between Coenzyme Q10 powder and dementia, found Coenzyme Q10 powder may improve oxygen flow to the brain. However, Oxygen deprivation is linked to some types of dementia, including Alzheimer’s disease.

 

How Do You Use Coenzyme Q10 Powder

Coenzyme Q10 Powder is oil soluble, with relatively low solubility. To incorporate it into an oil, the oil should be gently heated to about 120°F (49°C) and the powder stirred into it, wherein it will readily dissolve. Due to its low solubility, it can precipitate out of solution in an oil over time.

 

How To Take Coenzyme Q10 Powder

As a dietary supplement, experts generally suggest to take Coenzyme Q10 Powder in the morning or afternoon, take it with food. It can be absorbed most efficiently by the body if take Coenzyme Q10 Powder with a food containing some fat(such as peanut butter or salad with dressing). Do not take Coenzyme Q10 Powder close to bedtime, it may insomnia in some people. Taking Coenzyme Q10 Powder dosage 200 mg (about 1/10 tsp) up to three times daily, that is good. If you have a medical condition, are taking medication, are pregnant or nursing, always seek advice from a qualified healthcare professional before using any food supplement. Discontinue use if any adverse reaction occurs, as Coenzyme Q10 Powder should not be used as a substitute for a varied diet.


Side Effect On Coenzyme Q10 Powder

Coenzyme Q10 powder is LIKELY SAFE for most adults, with well-tolerate. It may interact with some blood pressure medications and some blood thinners, will deplete the body stores of CoQ10, these medications include statins, fibric acid derivatives, beta blockers, and tricyclic antidepressants. It may cause some mild side effects when you take Coenzyme Q10 powder,  including stomach upset, loss of appetite, nausea, vomiting, and diarrhea, cause allergic skin rashes in some people, also may cause lower blood pressure. So check your blood pressure carefully if you have very low blood pressure. Dividing the total daily Coenzyme Q10 powder dose by taking smaller amounts two or three times daily instead of a large amount all at once can help reduce Coenzyme Q10 powder side effects.

 

How to Store Coenzyme Q10 Powder

Coenzyme Q10 powder is a crystalline form, extremely susceptible to oxidation, a chemical reaction with the oxygen in air. If kept in contact with air, Coenzyme-Q10  powder will change from its usual bright orange color to a dark brown color., and will lose potency.

The best way to keep Coenzyme-Q10  powder tightly closed in a dry and well-ventilated place, store between 15°-30°C (59°-86°F) and away from sunlight. Do not freeze.

 

Reference

[1] Nihon Rinsho. 1998 Jan;56 Suppl 3:149-53. PMID: 9513406

[2] Nutr Rev. 2007 Jun;65(6 Pt 1):286-93. doi: 10.1301/nr.2007.jun.286-293. PMID: 17605305

[3] J Am Coll Nutr. 2001 Dec;20(6):591-8. doi: 10.1080/07315724.2001.10719063. PMID: 11771674

[4] Wu, Haiyou; Zhong, Zhangfeng; Lin, Sien; Qiu, Chuqun; Xie, Peitao; Lv, Simin; Cui, Liao; Wu, Tie (19 August 2020).

[5] Sharma, A; Fonarow, GC; Butler, J; Ezekowitz, JA; Felker, GM (April 2016). “Coenzyme Q10 and Heart Failure: A State-of-the-Art Review”. Circulation: Heart Failure. 9 (4): e002639

[6] Kagan, Daniel; Madhavi, Doddabele (2010). “A Study on the Bioavailability of a Novel Sustained-Release Coenzyme Q10-β-Cyclodextrin Complex”. Integrative Medicine. 9 (1).

 

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