|Product Name||Citicoline sodium|
|Synonyms||CITICOLINE SODIUM; |
Citicoline sodium salt;
IP 302 sodium.
|Appearance||White or crystalloid powder|
|Storage and Handling||Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).|
Why is Citicoline Sodium powder so popular?
Citicoline Sodium powder is a brain supplement that has received a lot of praise and attention recently. More and more individuals are interested in using natural compounds to help improve their memory and cognitive power.
Citicoline sodium powder is used as a prescription drug in some European and Asian countries to improve memory, thinking, and overall mental status among patients who have previously suffered from a stroke. However, with the advent of clinical research and studies on the compound, it was slowly become recognized in the field of health supplement manufacture as a potent nootropic ingredient.
What is Citicoline sodium powder?
Citicoline sodium powder, the CAS number is 33818-15-4 and its Molecular formula is C14H25N4NaO11P2. The molecular weight of the said compound is 510.31 g/mol.The purity of the compound ranges from 98% to 99%. It is generally soluble in water, solid in form, and is of white color in appearance.Citicoline sodium powder can be provided in bulk by AASraw.
Citicoline sodium is a dietary supplement ingredient believed to support cognitive functions, including focus, mood, and overall affect. It is also said to improve vision and accelerate physical and mental performance. Essentially, citicoline naturally occurs in the body and is found in brain cells and tissues. Medical experts say that citicoline plays a vital role in maintaining levels of neurotransmitters and other enzymes in the brain. Hence, it may its supplementation may be helpful to support vital bodily processes.
How Does Citicoline sodium Work?
Citicoline sodium (Cytidine diphosphocholine) is a neuroprotective compound commonly known as CDP choline. This compound is made up of choline and cytidine. Citicoline, which has a high amount of choline, aids in the transportation of dopamine and thereby increases its release into the brain. While choline is helpful to brain growth, it is only useful if cytidine is converted to uridine. It main works on us by four aspects:
❶Maintains neuronal cells integrity
Phospholipids are the essential compositions of cell membranes, which is necessary for the growth and repair of cells. Citicoline is a precursor for the synthesis of phospholipids (including phosphatidylcholine, phosphatidylserine, and phosphatidyl-ethanolamine). As cell membranes have a very high turnover rate, these phospholipids must be continuously synthesized to ensure the normal operation of cells, including brain cells and neuronal cells.
❷ Promotes healthy neurotransmitter production
In the brain, all brain cells communicate through synapses, while phospholipids are also essential to synaptic function. The primary phospholipid in the brain-phosphatidylcholine- makes up 30% of the gray matter, which is the information-processing center of the brain. Citicoline can increase the brain chemical – phosphatidylcholine and synthesize memory transfer factors—acetylcholine effectively.
Moreover, Citicoline Sodium increases norepinephrine and dopamine levels in the central nervous system.
❸ Boosts energy production in the brain
When at rest, the brain consumes about 20 percent of the entire body’s energy. The brain needs more power while performing strenuous mental activities, which has a high demand for cellular mitochondria.
Citicoline Sodium improves mitochondrial health to supply the energy for the brain through numerous mechanisms: maintaining healthy levels of cardiolipin (a phospholipid that is essential for mitochondrial electron transport in mitochondrial membranes); restoring mitochondrial ATPase activity; decreasing oxidative stress by inhibiting the release of free fatty acids from cell membranes.
❹ Protects the neuro
Citicoline Sodium powder can protect neural structures against free radical damage in the brain and promote a healthy inflammatory response through inhibiting the release of free fatty acids, decreasing breakdown of the blood-brain barrier, and attenuating arachidonic acid release.
Benefits Of Citicoline Sodium Powder
Taking pure Citicoline Sodium powder as presented in statements of customers in product reviews, provides several health benefits. These claims were also verified by scientific international researches conducted over the years. Some of the known features of using Citicoline Sodium are as follows:
Citicoline Sodium powder supports overall cognitive function: Aside from improving positive mood and enhancing memory, Citicoline Sodium supplementation is also believed to address other mental functions such as effective nerve signal impulse transmission and focus. Some experts also say that it may address some symptoms brought about by substance abuse.
Citicoline Sodium powder improves mood: A person’s mood is affected by imbalances in neurotransmitter production in the brain. The neurotransmitters primarily responsible for mood and affect are dopamine, norepinephrine, and serotonin. After crossing the blood-brain barrier, experts say that Citicoline Sodium helps improve dopamine and norepinephrine levels, thereby improving mood and promoting a positive outlook.
Citicoline Sodium powder enhances memory: Citicoline Sodium as a prescription drug has been evaluated as quite beneficial to address memory loss and brought about by stroke and other related disorders. Within recommended doses, pure Citicoline Sodium in dietary supplements is also believed to support memory work among adults. The compound, however, is not intended to diagnose, treat, cure or prevent other illnesses related to memory loss such as those secondary to traumatic psychiatric conditions.
The action of the ingredient in enhancing memory is brought about by its mechanism to increase the production of the neurotransmitter acetylcholine. Hence, some experts say that the ingredient may be helpful among elderly individuals who are diagnosed with Alzheimer’s disease and Dementia which often causes memory lapses.
In addition, there are also other benefits: Citicoline Sodium powder acts to protect nerve and brain cells. This is especially true in conditions where there is a low oxygen level known as oxidative stress. Some of the most often reported benefits in this area include improved visual acuity. Colors may seem brighter and sharper, with everything becoming clearer. In other cases, it may even enhance libido.
Citicoline Sodium Powder Side Effects
There are very few side effects associated with Citicoline Sodium powder. The supplement is generally well-tolerated and there are no known drug interactions. It is a natural compound after all that occurs in the body on its own. However, due to the possibility of significantly increased energy levels, it is not advisable to take Citicoline Sodium powder in the late afternoon or evening.
Some users may notice a bit of nerves or restlessness, elevated body temperature, and possibly some gastro-intestinal discomfort. If any of these side effects occur simply reduce the dosage or take a few days off (and then return by taking a lower initial dosage).
Where To Buy Bulk Citicoline Sodium Powder?
AASraw is a professional manufacturer of nootropic Citicoline Sodium Powder and support bulk order.Our monthy supply is 500kg and the production is stable.
Pure Citicoline Sodium powder price depends on quantity and shipment ways. What we can do for you is provide the best price and top quality Citicoline Sodium powder. For more details, welcome to talk with our sales at any time!
Reference Dinsdale JR, Griffiths GK, Rowlands C, Castelló J, Ortiz JA, Maddock J, Aylward M (1983). “Pharmacokinetics of 14C CDP-choline”. Arzneimittel-Forschung. 33 (7A): 1066–70.  Saver JL (Fall 2008). “Citicoline: update on a promising and widely available agent for neuroprotection and neurorepair”. Reviews in Neurological Diseases. 5 (4): 167–77.  Benson S, Arck PC, Tan S, Hahn S, Mann K, Rifaie N, Janssen OE, Schedlowski M, Elsenbruch S (Jun 2009). “Disturbed stress responses in women with polycystic ovary syndrome”. Psychoneuroendocrinology. 34 (5): 727–35.  Conant R, Schauss AG (Mar 2004). “Therapeutic applications of citicoline for stroke and cognitive dysfunction in the elderly: a review of the literature”. Alternative Medicine Review. 9 (1): 17–31. PMID 15005642.  Tardner, P. (2020-08-28). “Can Citicoline Cause Depression?: A review of the clinical literature • International Journal of Environmental Science & Technology”. International Journal of Environmental Science & Technology. Retrieved 2020-08-31.