Best Fisetin Powder (528-48-3) Manufacturer
AASraw produces Cannabidiol(CBD) powder and Hemp Essential Oil in bulk!

Fisetin Powder

Rating: Category:

AASRAW has the capacity to mass produce Fisetin Powder, 1930kg per month.

Product Description

Basic Characteristics

Product Name Fisetin Powder
CAS Number 528-48-3
Purity 65%-98% by HPLC
Molecular Formula C15H10O6
Formula Weight 286.24
Synonyms Natural Brown 1;

CI-75620;

NSC 407010;

BRN 0292829;

5-Deoxyquercetin;

2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one;

3,3′,4′,7-Tetrahydroxyflavone.

Appearance Yellow-green powder
Storage and Handling Stored in cool & dry places, protected from direct sunlight and heat.

 

Most people are worried about their health. They would do anything to improve their quality of life. Unfortunately, some people attempt to achieve this goal using the wrong methods. Instead, you should look for natural, alternative methods for dealing with your problems. This is why so many people are switching to plant remedies. Fisetin power is found in a variety of plants and Eudicotyledons. It can also be found in various trees and shrubs including the honey locust and parrot tree.

Furthermore, many fruits and vegetables contain this powder. It can be extracted from fruits and other herbal sources. So, what is Fisetin powder and what are the benefits of using this health supplement Fisetin powder?

 

What Is Fisetin Powder?

Fisetin powder is both a flavonoid and polyphenol that derives from vegetables, plants, and fruits. The substance is extracted from the natural pigment of cucumbers, onions, Eurasian smoke trees, apples, strawberries, and persimmons. Fisetin powder benefits overlap with some other flavonoids, including green tea catechins and quercetin. But it has its own unique set of biological properties. Fisetin powder has strong antioxidant and free-radical scavenging properties, which may promote healthy skin and brain health. Fisetin is a potent immune supporting agent.

 

Fisetin Powder Application

❶ Fisetin powder applied in the food field, it has become a new raw material which used in food and beverage industry.

❷ Fisetin powder applied in pharmaceutical field.

❸ Fisetin powder applied in cosmetic field, it owns the function of whitening, dispelling spot.

 

Fisetin Powder Health Benefits/Function

Fisetin powdernot only helps improve our immune system and prevent hyperdrive, we also know this nutrient helps protects the health of our nerves, though we aren’t quite sure how it does that .

Fisetin powder has been seen in the laboratory to have direct effects on our cells. It interacts with proteins on our cell membrane and regulates the ions that move in and out. These ions play a big role, and can influence the process of aging and even propagate diseases like cancer and diabetes. The regulation of these ion movements can also have a huge impact on the health of our nerves. In the lab, this small but mighty molecule has demonstrated effects that heal nerves, fight cancer and soothe inflammation. Here are some main health benefits of fisetin powder:

 

 Anti-Aging

Who knew that a strawberry smoothie could keep you young? Fisetin powder, as well as other flavonoids, are present in senolytic foods which help prevent aging. What is this senolytic power exactly? Well, first it’ s important to understand what senescence is. Senescence is the process of aging where our cells break down with time. This includes the breakdown of red blood cells that carry oxygen through our blood stream, as well as DNA damage that all our other bodily cells endure daily. The more DNA damage we have, the more cell death and dysfunction. Overall this plays a huge role in the process we know collectively as aging.

Plant flavonoids like Fisetin powder have been found to help slow down senescence. It’ s thought that it does this by stabilizing membrane proteins to help red blood cells from dying. It also helps reverse some of the DNA damage in our aging cells. With less DNA damage, cells grow and replicate. All of these effects can help us prevent many age-related diseases, such as osteoporosis, heart disease and the general frail-ness of old-age. Though all flavonoids have powerful effects against aging, it’ s been suggested in experiments that Fisetin powder is the strongest anti-aging compounds of them all.

 

 Regulates Blood Sugar

Fisetin powder can also help people suffering from diabetes in many different ways. Though research is limited, one study on diabetic rats found that month-long supplementation with Fisetin powder lowered blood sugar levels. Scientists aren’ t sure how it works, but it’ s possible that Fisetin powder helps regulate sugar production in the liver. Other studies have also mentioned preventative effects against diabetes-related damage to the kidneys, nerves and the heart. Fisetin powder supplementation also appears to help increase insulin secretion in diabetic rats.

 

 May Help Fight Cancer

Fisetin powder may fight cancer from multiple different angles. As an antioxidant, Fisetin powder, like other flavonoids, can reduce oxidative stress. It’ s unique chemical structure allows it to give electrical charges to damaging free-radicals, neutralizing them. This keeps them from damaging our genes and promoting cancer. Fisetin powder also hijacks cancer’ s unique ability to self-replicate indefinitely by blocking an “immortality” mechanism in the form of a protein enzyme called toiposomerase.

Additionally, Fisetin powder can help us fight chemo-resistant cancers. Some studies have found it effective in helping kill resistant colon cancer cells in the lab. It’ s possible that this special compound can actually disrupt survival mechanisms cancer cells use to survive through treatments. Though research is scarce, there seems to be interest in using Fisetin powder in combination with traditional therapies to treat a wide variety of cancers.

 

 Heart Health

Fisetin powder can also help improve your heart health. It improves circulation, reduces cholesterol, and protects our cardiovascular system from oxidative stress. One study found that Fisetin powder helps prevent complications that can develop after a heart attack. It does this by preventing inflammation that results in irregular scar tissue and cardiac muscle growth that can occur after heart attacks. Researchers used Fisetin powder injections for rats that had suffered a heart attack and found that rats that received the injection had better heart health overall. Additionally, rats receiving Fisetin powder had lower rates of developing heart attack related arrhythmias down the line.

 

 Skin Health

You can also see the benefits of Fisetin powder on your skin. Fisetin powder has been proposed to help improve collagen, reduce UV damage and even treat eczema. Researchers found that mice taking Fisetin powder were able to prevent skin inflammation and damage induced by UV rays. It also helped block the breakdown of collagen, which is the most important substance to keep skin youthful. As an antioxidant, it can also help neutralize oxidative stress that’s always a consequence of any UV light exposure. It also helps our skin form a healthier, stronger barrier against outside contaminants by promoting tighter seals between each skin cell.

 

 Cognitive Health

Fisetin powder not only helps you feel and look good, but helps you think faster too. If you’re suffering from any mood disorders or having memory problems, it’s time to give Fisetin powder a closer look. This special nutrient found in our everyday berries and vegetables can help us protect ourselves from diseases like Parkinson’s or Alzheimer’s. It does this by directly influencing the hippocampus, which is where our memories are stored. Fisetin powder helps prevent nerve damage by fighting toxins that can cause degradation. In animal studies, Fisetin powder has even been helpful in reducing the severity of Huntington’s disease.

 

Fisetin Powder Side Effects

Fisetin is generally thought to be very safe. However, due to the very limited number of human trials with fisetin, its safety profile in high doses is relatively unknown. The safety profile of fisetin in high doses is relatively unknown. Many studies involve cell cultures or animal tissues, while a limited number involve human tissues.In any case, irrespective of the known health benefits, pregnant women and children should avoid taking the fisetin supplements, due to lack of information of the side-effects of their use.

 

Further Fisetin Powder Studies

Fisetin powder has been studied prior to the interest in senolytics and, like many polyphenols, it has anti-inflammatory activity. While not all of the following studies are directly about aging per se, they do explore inflammation, which is a critical component of aging.

A 2018 study tested fisetin powder, curcumin, and three modified variants of these two compounds and discovered that they all reduced some biomarkers of aging, increased median lifespan in mice and flies, and reduced the signs of dementia. While the modified compounds worked somewhat better, the unmodified fisetin also worked. It also appears to have a potent effect on inflammation by blocking the activity of lipoxygenases, thus reducing the level of pro-inflammatory factors.

There also appears to be some potential for fisetin powder to address high blood sugar in diabetics. In a 2014 study, researchers discovered that it was able to block the inflammatory response to prevent damage to blood vessels and tissue in mice. Similar results were found for human cell lines tested during the same study.

A 2014 study found that it was an effective treatment for eczema in mice, as it was able to reduce the presence of immune cells such as T cells, mast cells, and eosinophils, which are commonly encountered in the skin lesions that eczema causes.

 

Summary

Fisetin powder is a compound found in many plants, including strawberries and apples. It is the most effective senolytic compared to a panel of flavonoids, removing aged, dysfunctional senescent cells in preclinical studies. This may help improve function in older age, shield against chronic disease, and increase healthy longevity.

In mice, fisetin alone extended lifespan by approximately 10%. Extensive research also demonstrates the potential of fisetin to help protect against cancer, stroke, obesity, type II diabetes, and other metabolic disorders.

A new fisetin formula compounds it with fenugreek, which protects it from inactivation in the gut. This allows more fisetin to be absorbed and distributed throughout the body for systemic benefits. More information, welcome to contact with the best Fisetin powder supplier-aasraw.

 

Reference

[1] Kim, G. D., Lee, S. E., Park, Y. S., Shin, D. H., Park, G. G., & Park, C. S. (2014). Immunosuppressive effects of fisetin against dinitrofluorobenzene-induced atopic dermatitis-like symptoms in NC/Nga mice. Food and Chemical Toxicology, 66, 341-349.

[2] Kwak, S., Ku, S. K., & Bae, J. S. (2014). Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo. Inflammation Research, 63(9), 779-787.

[3] Zoratti, L.; Karppinen, K.; Escobar, A.L.; Haggman, H.; Jaakola, L. (October 9, 2014).

[4] Iside C, Scafuro M, Nebbioso A, Altucci L (2020). “SIRT1 Activation by Natural Phytochemicals: An Overview”. Frontiers in Pharmacology. 11: 1225.

[5] Sadik, C. D., Sies, H., & Schewe, T. (2003). Inhibition of 15-lipoxygenases by flavonoids: structure–activity relations and mode of action. Biochemical pharmacology, 65(5), 773-781.

[6] Salmela, Anna-Leena; Pouwels, Jeroen; Varis, Asta; Kukkonen, Anu M.; Toivonen, Pauliina; Halonen, Pasi K.; Perälä, Merja; Kallioniemi, Olli; Gorbsky, Gary J.; Kallio, Marko J. (2009).

[7] Hwang ES, Song SB (2017). “Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells.

[8] Sahu, Bidya Dhar; Kalvala, Anil Kumar; Koneru, Meghana; Kumar, Jerald Mahesh; Kuncha, Madhusudana; Rachamalla, Shyam Sunder; Sistla, Ramakrishna (September 3, 2014).

 

AASraw is the trusted and legally licensed manufacturer of top quality Fisetin Powder. Welcome to place the order from us!