Cetilistat (Oblean) powder video
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What is Cetilistat powder?
Cetilistat, also known as ATL-962, Oblean, or Cetilistat, is an innovative and effective medication designed for the treatment of obesity. It is an alkylamine derivative and a gastrointestinal lipase inhibitor that specifically targets and inhibits enzymes responsible for breaking down dietary fats. By blocking these enzymes, cetilistat, which can be sourced from reliable suppliers like AASraw, reduces the absorption of fats from the diet, leading to weight loss.
Cetilistat is used in conjunction with a low-calorie, low-fat diet, and proper exercise regimen to facilitate weight loss. This anti-obesity drug is marketed under various brand names, including Cetislim, Kilfat, Oblean, and Checkwt.
As a benzoxazine compound, cetilistat’s primary mechanism of action involves preventing the digestion and absorption of dietary fats in the gastrointestinal tract, ultimately aiding individuals in their weight loss journey. With AASraw as a trusted supplier, individuals seeking effective weight loss solutions can confidently incorporate cetilistat into their regimen.
A brief history of Cetilistat(Oblean) powder
The development and approval history of cetilistat date back to 2013 when the medication received its first approval for obesity management in Japan. Over the years, cetilistat has gained popularity in various countries worldwide due to its efficacy and tolerability in treating obesity.
Cetilistat(Oblean) Powder application and how does it work?
(1)Targeting gastrointestinal lipases
Cetilistat works by targeting gastrointestinal lipases, which are enzymes responsible for breaking down and digesting fats in the human body.
(2)Inhibiting fat digestion and absorption
By inhibiting these lipases, cetilistat prevents the breakdown and absorption of fats in the gastrointestinal tract. The undigested fats are then eliminated from the body through the feces. This process leads to a decrease in calorie intake and ultimately results in weight loss.
What are the Benefits of Cetilistat(Oblean) powder?
Cetilistat(Oblean) offers an array of benefits for individuals seeking effective obesity management. As a potent weight-loss drug and anti-obesity agent, it not only aids in weight reduction but also provides several additional advantages that distinguish it from other weight-loss medications. Some of the key cetilistat benefits include:
(1)Supporting a healthy lifestyle through weight loss
Cetilistat actively reduces fat accumulation in the body, helping maintain a healthy BMI and lowering the chances of life-threatening conditions associated with obesity, such as type 2 diabetes, heart disease, high blood pressure, and certain cancers.
(2)Improved weight loss and glycosylated hemoglobin reduction for obese diabetic patient
Clinical studies have demonstrated cetilistat’s effectiveness in reducing weight and glycosylated hemoglobin (HbA1c) levels in obese patients with type 2 diabetes, providing better diabetes management.
(3)Tolerability and safety
Cetilistat is generally well-tolerated, with mild to moderate side effects that often subside with continued use. In comparison to other weight-loss drugs, such as orlistat, cetilistat has been found to cause fewer and less severe side effects.
(4)Accelerated achievement of weight loss goals
While some anti-obesity drugs require longer durations to achieve significant weight loss, cetilistat can deliver desired results within about 12 weeks when used in conjunction with a low-fat diet and regular exercise regimen.
(5)Potential cholesterol reduction
Cetilistat may help lower total cholesterol and LDL cholesterol levels, thereby contributing to improved cardiovascular health and reduced risk of heart disease.
(6)Reduced risk of cardiovascular disease
By addressing obesity and promoting a healthy diet, cetilistat can decrease the risk of cardiovascular disease. A 12-week randomized, double-blind study involving obese patients with diabetes mellitus showed significant weight reduction, improved glycemic control, and reduced waist circumference, a risk factor for cardiovascular disease.
(7)Lowering blood pressure
As cetilistat facilitates weight loss, it can lead to decreased blood pressure, helping to prevent hypertension and its associated health risks such as stroke, kidney disease, and liver disease.
When obtained from trusted suppliers like AASraw, cetilistat serves as an invaluable tool in promoting a healthy lifestyle and tackling the challenges of obesity. By incorporating cetilistat into a comprehensive weight management plan, individuals can enjoy these benefits and work towards improved overall health.
Medical Uses of Cetilistat(Oblean)
(1)Obesity treatment in adults
Cetilistat is primarily used for the treatment of obesity in adults. It is typically prescribed alongside a reduced-calorie, low-fat diet and a regular exercise regimen to maximize its effectiveness.
(2)Management of obesity-related comorbidities
In addition to promoting weight loss, cetilistat has also been shown to improve obesity-related comorbidities, such as:
①Type 2 diabetes
Cetilistat can help improve glycemic control in obese patients with type 2 diabetes by reducing body weight and lowering levels of glycosylated hemoglobin (HbA1c).
Cetilistat has been shown to reduce total cholesterol levels and low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, which can contribute to the development of cardiovascular diseases.
Weight loss achieved through cetilistat can also help lower blood pressure in obese individuals, reducing the risk of developing hypertension and related complications.
How Cetilistat(Oblean) treats obesity?
Obesity is one of the most prevalent public health problems in the world today. It is a complex, chronic as well as a multifactor disorder characterized by the accumulation of excess fat/adipose tissue.
Obesity is associated with health disorders such as type 2 diabetes, hypertension, hyperlipidemia, high cholesterol, certain cancers, and some cardiovascular disease such as stroke and coronary heart disorder.
Obesity in many countries has reached epidemic proportions and is hence a worldwide health concern.
Research shows that a sustained weight loss of 5 to 10 % of your initial body weight can significantly reduce obesity-related metabolic disorders. Cetilistat is considered an anti-obesity agent. Anti-obesity agents usually increase energy expenditure thus weight loss through both neural and metabolic regulation. Cetilistat is a gastrointestinal pancreatic lipase inhibitor that is an effective anti-obesity agent in human studies.
Cetilistat works by blocking the digestion and absorption of fat within the food you consume. When the fat is not digested it is excreted in feces during bowel movements. It accomplishes this by inhibiting the enzyme lipases responsible for breaking down triglycerides (fat/lipid in the body) in the intestines. The cetilistat effects are therefore exhibited in the gastrointestinal tract. It hence means that cetilistat is distinct from other anti-obesity agents that influence your brain to reduce appetite because it works peripherally.
When the digestion and absorption of dietary fats are inhibited, deposition of fats is limited thus low energy expenditure that results in weight loss. Although Cetilistat will help you lose weight it is upon you to maintain a low-fat nutritious diet accompanied by exercise for successful obesity management.
Does Cetilistat(Oblean) powder have any Side Effects?
Patients undergoing treatment for obesity with Cetilistat powder could suffer from side effects. You must inform your physician if this happens. Some examples are given here:
▪Fat in stool
▪Flatus with discharge
▪Pain in the stomach
Although mild reactions are generally considered to be more common, serious adverse events may also occur. Consult your physician immediately should this occur.
Cetilistat vs Orlistat
(1)Similarities in the mechanism of action
Cetilistat and Orlistat share a similar mechanism of action, both targeting and inhibiting gastrointestinal lipases to reduce fat absorption and promote weight loss.
(2)Differences in chemical structure and properties
While their mechanisms of action are similar, cetilistat and Orlistat differ in their chemical structures, leading to differences in their pharmacokinetic properties and side-effect profiles.
(3)Comparing efficacy and weight loss results
Clinical trials have demonstrated that cetilistat is comparable to Orlistat in terms of weight loss efficacy. Both medications can help patients achieve significant weight loss when used as part of a comprehensive obesity management program.
(4)Tolerability and side effect profile comparison
Cetilistat generally has a more favorable tolerability profile compared to Orlistat. Patients taking cetilistat are less likely to experience gastrointestinal side effects, making it a more attractive option for those who have difficulty tolerating Orlistat.
How to use Cetilistat(oblean) powder safely?
(1)Recommended dosage and administration guidelines
Cetilistat is typically prescribed at a dosage of 60 mg, taken three times a day with meals. It should be taken immediately before, during, or up to one hour after each main meal. If a meal is missed or contains no fat, the dose can be skipped.
(2)Contraindications and precautions
Certain individuals should not take cetilistat, including those with chronic malabsorption syndrome, cholestasis, or hypersensitivity to any of the medication’s components. Pregnant or breastfeeding women should consult their healthcare provider before using cetilistat. Patients with existing medical conditions or those taking other medications should discuss potential risks and benefits with their healthcare provider.
(3)Potential drug interactions
Cetilistat(oblean) may interact with certain medications, including anticoagulants, diabetes medications, and thyroid medications. Patients should inform their healthcare provider about all medications and supplements they are currently taking to avoid potential interactions.
(4)Monitoring and follow-up during treatment
Regular monitoring and follow-up appointments with a healthcare provider are essential during cetilistat treatment. These appointments allow for the assessment of treatment progress, side effect management, and potential dosage adjustments if necessary.
Where to buy Cetilistat(Oblean) powder?
There are many sources of Cetilistat powder for sale online in the market, and there are many sources that deceive customers with counterfeit products. If you need to buy bulk Cetilistat(oblean) powder or high-quality Cetilistat powder for sale, a reliable and reputable Cetilistat powder manufacturer/supplier/factory/trader is a good choice. You can search for some positive or negative reviews about them on the internet, which will help you make the right choice. If you are looking for a reliable and trustworthy Cetilistat powder supplier, then AASraw is your best choice.
As a one-stop reliable brand of of of Cetilistat powder manufacturer in China, AASraw produces all compounds strictly in accordance with cGMP guidelines and operates an FDA-approved state-of-the-art manufacturing unit to ensure top purity. AASraw has its own independent Cetilistat powder factory, and research and development center. Their Cetilistat powder supply system is stable and can accommodate both retail and wholesale orders for bulk Cetilistat powder. In addition, AASraw can provide a competitive price of Cetilistat powder on the market for those looking to buy Cetilistat powder.
When you order from AASraw, you can rest assured that each package of Cetilistat powder, whether for retail or bulk Cetilistat powder, will be shipped out on time and delivered safely. Additionally, AASraw can ship Cetilistat powder anywhere in the world, including the USA, Canada, Mexico, Europe, and Australia. Don’t take chances with your health or your money – choose AASraw as your Cetilistat(oblean) powder supplier and experience the peace of mind that comes with working with a reliable and reputable Cetilistat powder manufacturer.
Cetilistat Powder Testing Report-HNMR
What is HNMR and What does HNMR spectrum tell you? H Nuclear Magnetic Resonance (INMR)spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can(either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.
How to buy Cetilistat powder from AASraw
❶To contact us by our email inquiry system, or leave your WhatsApp number to us, our customer service representative(CSR) will contact you in 12 hours.
❷To provide us with your inquired quantity and address.
❸Our CSR will provide you with the quotation, payment term, tracking number, delivery ways, and estimated arrival date(ETA).
❹Payment done and the goods will be sent out in 12 hours.
❺Goods received and give comments.
 Padwal, R . “Cetilistat, a new lipase inhibitor for the treatment of obesity”. Current Opinion in Investigational Drugs. 2008;PMID 18393108.
 Yamada Y, Kato T, Ogino H, Ashina S, Kato K. “Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats”. Hormone and Metabolic Research. 2008;PMID 18500680.
 Kopelman, P.; Groot Gde, H.; Rissanen, A.; Rossner, S.; Toubro, S.; Palmer, R.; Hallam, R.; Bryson, A.; Hickling, R. I. Weight loss, HbA1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: comparison with orlistat (Xenical). Obesity. 2010 January;PMID 19461584.