Entecavir hydrate powder (209216-23-9) ≥98% | AASraw R&D Reagents
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Entecavir hydrate powder

Rating: SKU: 209216-23-9. Category:

AASraw is with synthesis and production ability from gram to mass order of Entecavir hydrate powder (209216-23-9), under CGMP regulation and trackable quality control system.

Product Description


Entecavir hydrate powder video




Raw Entecavir hydrate powder basic Characters


Name: Entecavir hydrate powder
CAS: 209216-23-9
Molecular Formula: C12H17N5O4
Molecular Weight: 295.29
Melt Point: 220-225°C
Storage Temp: -20°C Freezer
Color: White to off white Crystalline powder



Raw Entecavir hydrate powder in usage





Entecavir hydrate powder Usage

Entecavir hydrate powder is a potent deoxyguanosine nucleoside analog with antiviral activity selective for hepadnaviruses (EC50 = 3.7 nM against the hepatitis B virus (HBV) in cultured 2.2.15 liver cells). In vitro, the active intracellular form of Entecavir hydrate raw powder, Entecavir hydrate powder triphosphate, demonstrates a higher binding affinity for HBV DNA polymerase than the natural guanosine triphosphate substrate and effectively inhibits HBV DNA replication at 3 stages in the replication pathway: priming, reverse transcription, and DNA-dependent DNA synthesis. The potential therapeutic benefits of Entecavir hydrate raw powder have been demonstrated in woodchuck and duck models of HBV. Activity was confirmed in phase I/II preclinical studies and Entecavir hydrate powder received approval from the U.S. Food and Drug Administration for the treatment of adults with chronic hepatitis B.

Entecavir hydrate raw powder (ETV), sold under the brand name Baraclude, is an antiviral medication used in the treatment of hepatitis B virus (HBV) infection. In those with both HIV/AIDS and HBV antiretroviral medication should also be used. Entecavir hydrate powder is taken by mouth as a tablet or solution.

Common side effects include headache, nausea, high blood sugar, and decreased kidney function. Severe side effects include enlargement of the liver, high blood lactate levels, and liver inflammation if the medication is stopped. While there appears to be no harm from use during pregnancy, this use has not been well studied. Entecavir hydrate raw powder is in the nucleoside reverse transcriptase inhibitors (NRTIs) family of medications. It prevents the hepatitis B virus from multiplying by blocking reverse transcriptase.

Entecavir hydrate powder is mainly used to treat chronic hepatitis B infection in adults and children 2 years and older with active viral replication and evidence of active disease with elevations in liver enzymes. It is also used to prevent HBV reinfection after liver transplant and to treat HIV patients infected with HBV. Entecavir hydrate rawpowder is weakly active against HIV, but is not recommended for use in HIV-HBV co-infected patients without a fully suppressive anti-HIV regimen[9] as it may select for resistance to lamivudine and emtricitabine in HIV.

The efficacy of Entecavir hydrate powder has been studied in several randomized, double-blind, multicentre trials. Entecavir hydrate powder by mouth is effective and generally well tolerated treatment.

Entecavir hydrate raw powder is taken by mouth as a tablet or solution. Doses are based on a person’s weight. The solution is recommended for children more than 2 years old who weigh up to 30 kg. Entecavir hydrate powder is recommended on an empty stomach at least 2 hours before or after a meal, generally at the same time every day. It is not used in children less than 2 years old. Dose adjustments are also recommended for people with decreased kidney function.


Warning on Entecavir hydrate powder

The majority of people who use Entecavir hydrate powder have little to no side effects. The most common side effects include headache, fatigue, dizziness, and nausea. Less common effects include trouble sleeping and gastrointestinal symptoms such as sour stomach, diarrhea, and vomiting.

Serious side effects from Entecavir hydrate raw powder include lactic acidosis, liver problems, liver enlargement, and fat in the liver.

Laboratory tests may show an increase in alanine transaminase (ALT), hematuria, glycosuria, and an increase in lipase. Periodic monitoring of hepatic function and hematology are recommended.


Further instructions

Entecavir hydrate powder is a synthetic analog of 2-deoxyguanosine with antiviral activity against hepatitis B virus (HBV). Entecavir hydrate raw powder ris activated in vivo to a 5-triphosphate metabolite. In turn, the triphosphate form competes with the natural substrate deoxyguanosine triphosphate (dGTP) for incorporation into viral DNA. The incorporation of the activated triphosphate metabolite of Entecavir hydrate powder inhibits the reverse transcriptase (RT) viral RNA-dependent HBV DNA polymerase and, so, the replication of viral DNA and transcription.

Entecavir hydrate raw powder is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir hydrate powder therapy can be associated with flares of the underlying hepatitis B during or after therapy, but has not been linked to cases of clinically apparent liver injury.


Entecavir hydrate Raw Powder

Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order(Within 1kg)can be sent out in 3 workingdays after payment.

Entecavir hydrate powder Marketing

To be provided in the coming future.



How to buy Entecavir hydrate powder from AASraw


1.To contact us by our email inquiry system,or online skypecustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.