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Eplerenone powder (107724-20-9)

Rating: SKU: 107724-20-9. Category:

AASraw is with synthesis and production ability from gram to mass order of Eplerenone powder (107724-20-9), under CGMP regulation and trackable quality control system.

Eplerenone powder is an aldosterone antagonist more specific for the mineralocorticoid receptor than spironolactone, having lower affinity for progesterone, androgen, and glucocorticoid receptors. For improvement of survival of stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and clinical evidence of congestive heart failure after an acute myocardial infarction.

Product Description

 

Eplerenone powder video

 

 


 

Eplerenone powder basic Characters

 

Name: Eplerenone powder
CAS:  107724-20-9
Purity :  99%min (HPLC)
Molecular Formula:  C24H30O6
Molecular Weight:  414.49
EINECS: 1308068-626-2
Synonyms: pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-lactone methyl ester;EPLERENONE 98%;EPLERENONE USP STANDARD;Elperenone;EplerenoneC24H3006;pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo, γ-lactone, methyl ester (7 α, 11 α, 17 α);EPLERENONE AND N-1 INTERMEDIATE;epoxymexrenone
Melt Point: 241-243°C
Alpha: D +5° (c = 0.437 in chloroform)
Storage Temp: Store at RT
Solubility DMSO: soluble2mg/mL, clear (warmed)
Color: White to off-white crystalline powder

 


 

What You Want To Know On Eplerenone powder

 

Name

Eplerenone powder(AASraw)

 

What is Eplerenone powder

Eplerenone powder is an oral aldosterone receptor antagonist similar to diuretic spironolactone, it can be used alone or in combination with other medicines to treat high blood pressure. It works by blocking a chemical (aldosterone) in your body which in turn lowers the amount of sodium and water the body retains. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. It is also used to treat congestive heart failure following a heart attack. Besides, Eplerenone powder is being explored as a treatment for central serous retinopathy.

 

How is Eplerenone powder best taken

Using Eplerenone powder as ordered by your doctor, usually once or twice daily. Follow the directions on your prescription label, use this medication regularly in order to get the most benefit from it. Remember to use it at the same time(s) each day. The dosage is based on your medical condition (high blood pressure, heart failure), response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Your doctor may occasionally change your dose to make sure you get the best results.Eplerenone powder may be taken with or without food.To be sure this medication is helping your condition and is not causing harmful effects, your blood pressure will need to be checked on a regular basis. Your potassium levels will also need to be checked with frequent blood tests. Visit your doctor regularly.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

 

Warning on Eplerenone powder

Eplerenone powder should be used with caution in:

patients with kidney or liver disease, those taking lithium (generally given for bipolar disorder), and those taking tacrolimus or ciclosporin (used to prevent organ rejection after a transplant or treat skin conditions such eczema).
It should not be used in:

patients who are allergic (hypersensitive) to Eplerenone powder or to any other ingredients in the medication (such as lactose), patients who have high levels of potassium in the blood (hyperkalaemia), those with moderate to severe kidney disease, those with severe liver disease, children, patients taking medicines for fungal infection (ketoconazole or itraconazole), antiviral medication for HIV (nelfinavir or ritonavir), antibiotics (clarithromycin or telithromycin), nefazodone for depression, or drugs to help the body excrete excess fluid such as potassium sparing diuretics and ‘salt tablets’ (potassium supplements).

Before taking Eplerenone powder, let your doctor know if you have, or have ever had:
Diabetes

  • Have poor kidney function(Kidney disease)
  • Allergies to any medication
  • High potassium levels in your blood (hyperkalemia)
  • severe kidney disease(Liver disease)
  • High cholesterol or triglyceride levels
  • Gout (a type of arthritis caused by a buildup of uric acid crystals in the joints)

Patients who are allergic (hypersensitive) to Eplerenone powder or to any other ingredients in the medication (such as lactose), patients who have high levels of potassium in the blood (hyperkalaemia), those with moderate to severe kidney disease, those with severe liver disease, children, patients taking medicines for fungal infection (ketoconazole or itraconazole), antiviral medication for HIV (nelfinavir or ritonavir), antibiotics (clarithromycin or telithromycin), nefazodone for depression, or drugs to help the body excrete excess fluid such as potassium sparing diuretics and ‘salt tablets’ (potassium supplements)

Your doctor may recommend that you adopt a low-salt diet during your treatment with Eplerenone powder. Follow these instructions carefully. Tell your doctor you’re taking this medicine before having any type of medical or dental procedure. Keep all appointments with your doctor and laboratory while using Eplerenone powder. Your healthcare provider will want to perform frequent tests to check your body’s response to this drug. Certain drugs shouldn’t be used along with Eplerenone powder. Tell your doctor if you’re taking any of the following:

  • Midamor (amiloride)
  • Dyrenium (triamterene)
  • Nizoral (ketoconazole)
  • Pregnancy and Eplerenone powder
  • Aldactone (spironolactone)
  • Amiloride and hydrochlorothiazide
  • Sporanox or Onmel (itraconazole)
  • Aldactazide (spironolactone and hydrochlorothiazide)
  • Dyazide or Maxzide (triamterene and hydrochlorothiazide)
  • Potassium supplements, or salt substitutes that contain potassium

Before starting on Eplerenone powder, tell your doctor if you’re pregnant, or plan to become pregnant. You’ll need to discuss the benefits and risks of taking this medicine during pregnancy. As it’s not known whether Eplerenone powder passes into breast milk. Don’t breastfeed a baby while using this medicine.

 

Eplerenone powder

Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order(Within 1kg)can be sent out in 3 workingdays after payment.

 

Eplerenone powder Marketing

To be provided in the coming future.

 


 

How to buy Eplerenone powder from AASraw

 

1.To contact us by our emailblank inquiry system,or online skypeblankcustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.