Raw Fasoracetam powder (110958-19-5) hplc≥98% | AASraw Nootropics
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Fasoracetam powder

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AASraw is the professional manufacturer of Fasoracetam raw powder which has independent lab and large factory as support, all production will be carried out under CGMP regulation and trackable quality control system. The supply system is stable, both retail and wholesale orders are acceptable.Welcome to order from AASraw!

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Product Description

1. Fasoracetam Powder Video-AASraw

 


2. Raw Fasoracetam Powder Basic Characters

Name: Fasoracetam powder
CAS: 110958-19-5
Molecular Formula: C14H27N3O2
Molecular Weight: 158.15
Melt Point: 160-166°C
Storage Temp: Store at room temperature or cooler
Color: White or off-white powder

 


3. Raw Fasoracetam Powder Testing Report-HNMR

Fasoracetam-110958-19-5-NMR-Spectrum

What is HNMR and What does HNMR spectrum tell you? H Nuclear Magnetic Resonance (NMR) spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.

4. What is Fasoracetam Powder?

Fasoracetam is a synthetic nootropic belonging to the racetams. A Japanese pharmaceutical company initially developed it for treating vascular dementia, but a lack of efficacy stopped its further development.

However, it is has recently reappeared in clinical trials, with research looking at its potential for treating different psychiatric disorders and improving general cognition.

The initiative has been taken up by Aevi Genomic Medicine that began clinical trials to investigate how this drug may affect people on the autism spectrum disorder, those with attention deficit hyperactivity disorder (ADHD), and anxiety.

5. How Does Fasoracetam work in the brain?

Fasoracetam works by interacting and modulating three critical neurochemical systems: the glutamatergic, cholinergic, and gabaergic systems.

All three can work in the capacity of a cognition enhancer with potential benefits like an improvement in cognitive function, reduced brain fog, and enhanced mental clarity.

Like other nootropic substances, fasoracetam increases acetylcholine levels. This cholinergic action helps enhance cognition, memory, focus, mood, alertness, neuroplasticity, and long-term memory.

At the same time, it also inhibits acetylcholine breakdown by cholinesterase, encouraging its uptake by cholinergic receptors.

The other neurotransmitter it works on is gamma-aminobutyric acid (GABA) by upregulating GABA (B) receptors.

GABA receptors are present throughout the central nervous system and, when activated, trigger excessive excitation inhibition in the central nervous system.

In other words, GABA soothes neurons to promote a sensation of calm and contentment. In addition, these mechanisms assist GABA to overcome anxiety, fear, sleep disorders, and depression.

The third mechanism involves the glutamate system. Fasoracetam also modulates primary metabotropic glutamate receptors, affecting cognitive functions, neuroprotection, synaptic plasticity, and general anxiety.

Imbalances of the neurotransmitter glutamate imbalances can be linked to several mental and physical disorders, including depression, ADHD, epilepsy, and Alzheimer’s disease, to name a few.

6. The Benefits of Fasoracetam

  • May Improve Memory and General Cognition

In animal testing, fasoracetam effectively prevented or reduced artificially induced amnesia and forgetfulness.‍

Though there is no publicly available data on similar experiments on human subjects, many users say they experience substantial memory improvement when taking it.‍

Like other racetam nootropics, fasoracetam increases the amount of acetylcholine, the neurotransmitter most responsible for memory, learning, and cognition.‍

  • May Relieve Anxiety and Depression

Fasoracetam may improve mood, reduce anxiety, and lift depression by acting on two of the brain’s most powerful mood-influencing chemicals, glutamate and gamma-aminobutyric acid (GABA).‍

By simultaneously up-regulating GABA, which is an inhibitory neurotransmitter, and suppressing the excess production of the excitatory neurotransmitter glutamate, fasoracetam provides what users describe as a smooth, non-jittery feeling of improved mood, relaxation, and calmness.

There are no publicly available studies on fasoracetam’s effect on mood, anxiety, or depression in humans, but many users report that they feel calmer, less anxious, and less depressed when taking it.‍

  • Potential ADHD Treatment

One of the few publicly available human studies on fasoracetam suggests that it may be a potential treatment for ADHD.‍

The study, which involved 30 subjects between the ages of 12 and 17, tested the efficacy of fasoracetam in treating ADHD among adolescents who demonstrated a specific mutation in the glutamatergic gene network. This mutation is strongly associated with ADHD and is present in a significant percentage of adolescents with the disorder.

The subjects who took fasoracetam over the five weeks of the study showed marked improvement in all clinical measures during the trial. Reduction of ADHD symptoms persisted in post-trial testing, and none of the study participants demonstrated the development of either tolerance or dependence.

7. Fasoracetam used for improving cognitive function

Fasoracetam has been found to be ineffective for combating pathological memory impairment resulting from conditions such as dementia or Alzheimer’s Disease. More generally, fasoracetam seems to be ineffective for slowing age-related cognitive decline and for ameliorating any kind of vascular-related cognitive impairment.

That said, animal studies suggest that fasoracetam may be effective for promoting memory function. In the already-cited study – see reference [1] – researchers found that fasoracetam administration was able to reverse memory impairment induced by GABA receptor agonists. This study was performed on rodents, but the same mechanism exists in humans; it makes sense that reducing GABA receptor activity (or reversing GABA receptors agnoists) would improve memory function.

8. Where to buy Fasoracetam Powder?

Our review shows that fasoracetam shows a great deal of promise for managing neurological disorders such as ADHD symptoms, autism spectrum disorder, and anxiety.

It also provides benefits for improving different areas of overall cognition, such as improving focus and concentration, minimizing memory disruption, and improving memory recall, all without the risk of tolerance or dependence. This sums up everything quality nootropics promise for enhancing brain function.

9.Reference:

[1] “Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling”. ResearchGate. Retrieved 2020-10-16.

[2]Malykh, AG; Sadaie, MR (12 February 2010). “Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders”. Drugs. 70 (3): 287–312.

[3] Tardner, P. “Fasoracetam as a treatment for ADHD: A systematic review of available clinical data•International Journal of Environmental Science & Technology. Retrieved 2020-10-16.

[4]”Press Release: Medgenics, Inc. Announces Name Change to Aevi Genomic Medicine, Inc”. Aevi via MarketWired. 16 December 2016.

[5]Moskowitz, D. H. (2017). Finding the Genetic Cause and Therapy for ADHD, Autism and 22q. BookBaby (self published). ISBN 9781483590981.

10. How to buy Fasoracetam Powder from AASraw?

❶To contact us by our email inquiry system,or leave your whatsapp number to us, our customer service representative(CSR) will contact with you in 12 hours.
❷To provide us your inquired quantity and address.
❸Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
❹Payment done and the goods will be sent out in 12 hours.
❺Goods received and give comments.


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