Isoproterenol HCL video
Isoproterenol HCL basic Characters
|Melt Point:||165-175 °C|
|Color:||white crystalline powder|
Isoproterenol HCL (949-36-0) usage in cycle
asthpul ;dl-isadrinehydrochloride ;dl-isoprenalinehydrochloride ;dl-isopropylnoradrenalinehydrochloride ;dl-isopropylnorepinephrinehydrochloride ;dl-n-isopropylnoradrenalinehydrochloride ;racemicisoprenalinehydrochloride ;racemicisoproterenolhydrochloride,Isoproterenol HCL (CAS 949-36-0)
Isoproterenol Hydrochloride is the hydrochloride salt form of isoproterenol, a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on the beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and cardiac output. In addition, isoproterenol acts on beta-2 adrenergic receptors in bronchiolar and vascular smooth muscle, thereby causing smooth muscle relaxation.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. Isoproterenol hydrochloride is used mainly as bronchodilator and heart stimulant.
Isoproterenol hydrochloride injection, by increasing myocardial oxygen requirements while decreasing effective coronary perfusion, may have a deleterious effect on the injured or failing heart. Most experts discourage its use as the initial agent in treating cardiogenic shock following myocardial infarction. However, when a low arterial pressure has been elevated by other means, isoproterenol hydrochloride injection may produce beneficial hemodynamic and metabolic effects.
In a few patients, presumably with organic disease of the AV node and its branches, Isoproterenol HCL (CAS 949-36-0) injection has paradoxically been reported to worsen heart block or to precipitate Adams- Stokes attacks during normal sinus rhythm or transient heart block.
-Isoproterenol hydrochloride used for
Use for treatment of heart block and Adams-Stokes attacks.Also has been used for treatment of ventricular arrhythmias secondary to AV nodal block and carotid sinus hypersensitivity.a However, evidence supporting benefit in patients with cardiac arrhythmias generally lacking; safer and more effective alternatives such as cardiac pacing and other drug therapies are available.
Has been used in the treatment of cardiac arrest until defibrillation or emergency pacemaker therapy could be employed. However, experts state that isoproterenol is not a drug of choice in ACLS and should only be considered in this setting for treatment of symptomatic bradycardia unresponsive to atropine or as a temporary measure until pacemaker therapy can be instituted.Should not be used for resuscitation in patients with cardiac arrest or hypotension because of potential deleterious effects (e.g., exacerbation of ischemia, arrhythmias, peripheral vasodilation).
Must not be administered to patients with acetylcholinesterase-induced bradycardias; however, may be beneficial at high doses in refractory bradycardia caused by β-adrenergic blocking agents.
-Isoproterenol hydrochloride dosage
*Select dosage and method of administration according to patient response and specific clinical situation.
*Initiate therapy at lowest recommended dose and increase gradually, if necessary, while monitoring the patient.
*Adjust dosage according to clinical and hemodynamic parameters including heart rate, central venous pressure, systemic BP, and urine output.
-Isoproterenol hydrochloride drug interactions
Isoproterenol HCL (949-36-0) injection and epinephrine should not be administered simultaneously because both drugs are direct cardiac stimulants and their combined effects may induce serious arrhythmias. The drugs may, however, be administered alternately provided a proper interval has elapsed between doses.
Avoid ISUPREL when potent inhalational anesthetics such as halothane are employed because of potential to sensitize the myocardium to effects of sympathomimetic amines.
Isoproterenol hydrochloride Raw Powder
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