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Letrozole powder

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AASraw is the professional manufacturer of pure Letrozole(Femara) raw Powder which has independent lab and large factory as support, all production will be carried out under CGMP regulation and trackable quality control system. The supply system is stable, both retail and wholesale orders are acceptable.Welcome to order from AASraw!

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Product Description

1. Raw Letrozole(Femara) Powder Basic Characters

Name:  Letrozole
CAS: 112809-51-5
Molecular Formula: C17H11N5
Molecular Weight: 285.31
Melt Point: 181-183°C
Storage Temp: RT
Color: White or off white Crystalline powder

 


2. Letrozole(Femara) Powder Testing Report-HNMR

Letrozole (Femara) powder HNMR

What is HNMR and What does HNMR spectrum tell you? H Nuclear Magnetic Resonance (NMR) spectroscopy is an analytical chemistry technique used in quality control and research for determining the content and purity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion.

3. History of Letrozole/Femara?

Letrozole is a hormone therapy drug used to treat breast cancer in women who have gone through a natural menopause (when periods stop). It can also be used in premenopausal women having ovarian suppression (treatment to stop the ovaries working). Men with breast cancer may be given letrozole , although another drug called tamoxifen is more commonly used.

You may also hear it called Femara, which is its best-known brand name. There are a number of other brands of letrozole, all of which contain the same dose of the Letrozole Powder.

Legally, letrozole is only available with a doctor’s prescription. However, there are websites that sell Letrozole Powder online and other performance-enhancing drugs. It is very convenient now to buy Letrozole Powder online. It will be important to choose the reliable supplier such as AASRAW factory.

4. What is Letrozole(Femara) Powder?

Letrozole Powder is an anti-estrogen and one of the most potent Aromatase Inhibitor. It is commonly sold under the brand name Femara among others. Now It is used by many bodybuilders during post cycle therapy (PCT) and complements other anabolic steroids or prohormones. Letrozole Powder helps the body get back to its normal stage and stabilize the hormonal levels.

5. Letrozole Powder mechanism of action: How does it work?

Letrozole is an aromatase inhibitor, meaning that it blocks an enzyme responsible for a key step in the formation of estrogens. More specifically, the enzyme aromatase is responsible for the conversion of androgens (e.g., testosterone) into estrogens. Letrozole inhibits this process, which reduces the amount of estrogen in the body.

Letrozole is in medications used to fight estrogen-dependent breast cancer in women. Letrozole lowers the levels of estrogen in the body. Estrogens stimulates some breast cancers to grow. These breast cancers are called hormone sensitive or hormone receptor positive. By decreasing the amount of estrogen in the body, letrozole can slow or stop the growth of some types of breast cancer cells that need estrogen to grow. Letrozole only works in women who have had their menopause.

6. What is Letrozole Powder used for?

Letrozole Powder is used for treating certain type of breast cancer among post-menstrual women. It can be combined with Tamoxifen. It is also used to treat aromatization issues in the anabolic steroid users. Mostly, anabolic users consider Letrozole Powder as a crucial PCT substance.

Letrozole Powder is used for treating breast cancer

Letrozole Powder is a medicine used for treating breast cancer. It can also help prevent breast cancer coming back.

It is mainly prescribed for women who have been through the menopause and have a type of cancer called “hormone-dependent” breast cancer.

Most people who take Letrozole Powder will have had surgery, radiotherapy or sometimes chemotherapy to treat their breast cancer first.

Letrozole Powder comes as tablets. Mostly, it is available on prescription only. Due to the popularity of steroid powder, Buy Legal Femara Powder online become possible. You can select the reliable steroid powder manfaucturer you like. Just need to ensure they supply the high quality product. AASRAW is one of the top supplier you don’t want to miss. Start your Letrozole powder PCT cycle from here with us.

Letrozole Help Improve Fertility?

AASraw Letrozole Powder helps to improve fertility in two main ways,

  • inducing ovulation and
  • increasing the number of eggs released each cycle.

Femara Powder to Induce and Increase Ovulation

Letrozole Powder encourages the ovaries to ovulate by producing more natural stimulation. Femara Powder improves ovulation by blocking estrogen production, which causes the body to release higher than normal levels of follicle-stimulating hormone (FSH). The additional levels of FSH stimulate ovarian follicle(s) to develop and mature in the ovary. For women who don’t ovulate regularly or who have Polycystic Ovarian Syndrome (PCOS), the increased amounts of FSH can help to produce mature follicle(s) and egg(s), so ovulation can occur.

For women without ovulatory issues, Letrozole Powder can cause them to develop multiple mature follicles, which release more than one eggs for ovulation.

Research has shown that AASraw Letrozole Powder can also be beneficial to induce ovulation for women who have previously failed with Clomid or are considered “Clomid Resistant.”  In one study, Letrozole Powder significantly helped to improve ovulation rates and live birth rates for women who have failed to ovulate with Clomid.

Letrozole Powder uses for (Multiple) Egg Development

Femara Powder can increase the number of eggs released each cycle by increasing the number of follicles that develop. In a normal ovulatory cycle, one follicle develops, and one egg is released. In a Femara Powder medicated cycle, the amount of FSH a woman produces increases which may cause multiple follicles to develop and multiple eggs to be released, especially for women who ovulate regularly. The release of multiple eggs gives a better chance for fertilization to occur. Medicated cycles that result in the development of multiple follicles and eggs are referred to as controlled ovarian stimulation cycles.

Letrozole Powder uses as PCT in bodybuilding

Athletes who take anabolic steroids might use an aromatase inhibitor like Letrozole Powder to prevent the formation of estrogens, and therefore reduce or prevent the unwanted and feminizing effects of anabolic steroid use. These Femara Powder side effects include male breast development (gynecomastia), water retention, and belly fat. In addition, male athletes may use abuse aromatase inhibitors like Letrozole Powder to boost their own natural levels of testosterone by preventing its breakdown.

7. Benefits Of Letrozole Powder For Men

For some user, Letrozole Powder, Clomid, and Nolvadex are a case of comparing apples and oranges. Although roughly the same thing, that has different effects, durations, and outcomes.

lf you’re concerned about gyno specifically, then Letrozole Powder will work best. Its nuclear fuel forsteroid users who are suffering from gyno, and it can actually reverse the symptoms.

SERMs are also a great choice for bouncing testosterone levels back. Clomid or Nolvadex will bounce your levels back by around 60% from baseline in as little as a month. For general bounce back, these are better than Letrozole Powder.

As a bodybuilder, Letrozole Powder benefits can be attractive because not only does it block this conversion and therefore reduce estrogen levels while allowing the testosterone to rise, but it can also prevent water retention which will lead to a harder, drier look to your muscle tissue. Remember, always buy high quality Letrozole Powder, that is the precondition to get promised Letrozole Powder benefits it has. AASraw Letrozole Powder supplier, contact us now.

Overall, l had a great experience using Letrozole Powder uses for PCT, and online, there’s a lot of positive talk about Letrozole Powder benefits using it as well.

There is a bit of a contradiction that confuses people, in that aromatase inhibitors generally stop conversion, while SERMs are better at targeting estrogen receptors in certain tissues, especially the breast. And yet, amongst bodybuilders, AASraw Letrozole Powder is seen as best for gyno, when you would think the opposite was true and that Nolvadex/Clomid would be.

l think what this is mostly about is that it’s so potent at higher doses, that the general effects are so strong they shut down that gyno progress, and can even reverse it. On the other hand,Nolvadex and Clomid can be potent, but they don’t kick in so aggressively and maintain at the start, giving time for the gyno to progress.

8. What are the side effects to using Letrozole Powder?

The side effects of Letrozole Powder will cover a wide breadth and will be very similar to Arimidex. Both weakness and fatigue are two of the most common side effects of Letrozole Powder use. However, for the anabolic steroid user this will normally not be an issue. The use of anabolic steroids should prevent such states so as long as estrogen suppression isn’t taken too far. The exception would be its use during a hard bodybuilding contest prep cycle. During a harsh bodybuilding diet, the individual will normally be very weak and fatigue at the end of his diet due to tremendously intense training and very low caloric intake. Beyond possible energy issues, the most common Letrozole Powder use side effects include:

  • Headaches
  • High Blood Pressure
  • Hot Flashes
  • Joint Pain
  • Depression

Letrozole Powder has also been shown to have the ability to notably decrease bone mineral content, which could increase the risk of osteoporosis. This should, however, not be a big risk for the anabolic steroid as most steroids have the ability to promote bone mineral content to a degree, especially Nandrolone powder. As with all medications and anything we put into our body, the Letrozole Powder side effects will largely surround possible and not guaranteed. We are all different and respond to varying substances differently. This is something you need to keep in mind, and if the side effects of Letrozole Powder prove to be too much to handle, alternative medications should be looked at. Buy high-quality Letrozole Powder whenever possible to avoid unwanted Letrozole Powder side effects.

The final Femara Powder side effects surrounds cholesterol, specifically a reduction in HDL cholesterol. Alone it does not appear to have a strong, statistical impact, but for the anabolic steroid user this can be a concern. Many anabolic steroids already have the ability to negatively affect cholesterol, and when conjoined with an aromatase Inhibitor it appears to be greatly exasperated. Studies have shown that therapeutic doses of testosterone have very little negative effect on cholesterol but the same doses can suppress HDL cholesterol by as much as 25% when combined with an aromatase Inhibitor. When testosterone is administered at a supra physiological level, a minimal level of HDL suppression is normally expected. When the same dosing level is conjoined with an aromatase Inhibitor data shows that a 20% or greater suppression of HDL cholesterol is a very real possibility.

Due to the possible adverse effects on cholesterol, especially for the anabolic steroid user, a cholesterol friendly lifestyle becomes imperative. A healthy lifestyle will greatly revolve around your diet. Simple sugars and saturated fats should be limited and omega fatty acids should be a large part of your diet. Daily fish oil supplementation is recommended. Many may also find a cholesterol antioxidant supplement to be useful. Further, implementing plenty of cardiovascular activity into your routine is very important. Some type of daily cardiovascular activity is advised.

Because of the potential cholesterol issues, many bodybuilding users will need to use SERM’s to combat estrogenic side effects when possible. SERM’s won’t always get the job done, but they can work and will work a lot better than many steroid users believe. If an aromatase Inhibitor is needed, some have suggested that a daily dose of Nolvadex at 10mg per day with your aromatase Inhibitor could help protect cholesterol levels due to SERM’s actively promoting healthier cholesterol levels.

9. Letrozole Powder Dosage

The recommended dosage for Letrozole Powder depends on the reason you’re taking this drug for. For instance, the suggested dosage for women that take Letrozole Powder for breast cancer is completely different from those who take it purely as a bodybuilding supplement.

Letrozole Dosage During Anabolic Steroid Use

Making the mistake of taking too much Letrozole Powder during steroid use will have no benefit and bring about negative effects, like fatigue, of course buy high quality Letrozole(Femara) Powder also important. So it’s critical to maintain a sensible Letrozole Powder dosage.

With a medical dose usually around 2.5mg daily, we would look at no higher than that and most of the time even lower. To protect from estrogen related side effects during steroid use a dose of as low as 0.5mg to 1.25mg every two days is often enough for excellent estrogenic related protection for most men.

Only if you are experiencing early signs of gynecomastia would increasing the dose at this time up to 2.5mg per day can potentially even fully reverse the symptoms; but be prepared for a noticeable zap in energy during this time. Once gyno symptoms subside it’s important to reduce your Letrozole Powder dosage back down to regular estrogenic protection levels.

Female Letrozole Powder dosage

Increased estrogen levels is not anywhere near as great a concern for female steroid users as it is for males. The main reason for using an aromatase Inhibitor like Letrozole Powder by females would be to mitigate water retention, especially for competitive bodybuilders or physique athletes where this is most important.

In fact Letrozole Powder is not recommended as a first choice for females due to its potency in reducing estrogen so much, hence why it is not used medically by females who have not gone through menopause. Females who are determined to use Letrozole Powder are advised to dose at just 0.5mg every other day and gauge results and effects from there.

10. Who might be offered letrozole(Femara) Powder?

Letrozole Powder is suitable for women who have been through the menopause and whose breast cancer is oestrogen receptor positive.

Sometimes Femara Powder is given alongside ovarian suppression to women who haven’t yet been through the menopause.

If your cancer is hormone receptor negative, then Letrozole Powder will not be of any benefit.

11. Letrozole Powder vs Arimidex for PCT

Letrozole Powder and Arimidex powder are very similar compounds. Both are nonsteroidal aromatase inhibitors and both are favored by anabolic steroid users to prevent estrogenic side effects. Both drugs have a similar side effect risk profile. Out of the these two AIs, Arimidex generally takes the lead as being more widely used by bodybuilders but this can come down to a number of factors including availability, cost, and wanting to follow in the path of what friends and online acquaintances might recommend.

While both of these AIs can help stimulate natural testosterone production, neither are considered by most guys to be the right choice for PCT when used alone; in fact many people won’t use a powerful AI like Arimidex or Letrozole Powder during PCT at all and instead go for a SERM drug with Nolvadex being a popular choice, alongside Clomid and often HCG as well.

The main reason for this is that Arimidex powder is very good at lowering estrogen, and AASraw Letrozole Powder even more so. They are so powerful at this task that they can result in estrogen levels that are too low even for the male body. Buy Letrozole Powder wholesale from AASraw supplier, enjoy the bulk price.

This causes complications in the hormonal balance and will have a negative impact in your natural testosterone recovery; males still need a small amount of estrogen to keep things in balance and since PCT is all about getting your natural hormone function back to normal, continuing with a high estrogen suppression drug like Letrozole Powder or Arimidex after the steroid cycle can make this difficult, if not impossible.

Another issue when considering the use of Letrozole Powder during PCT is that when it is combined with the staple PCT drug of choice for most people, Nolvadex, a negative interaction occurs where the concentrations of drugs counteract each other. This is also an issue when Arimidex is combined with Nolvadex.

This is another reason why combining either of these AIs with a SERM during PCT is not advisable at all – and since a SERM is basically essential for PCT it is going to take priority over either Letrozole Powder or Arimidex. Both of these AIs offer far more advantages when their use is limited to during your steroid cycle where you can greatly benefit from their powerful anti-estrogen effects during that time.

12. Letrozole VS clomid

Clomid (clomiphene citrate) powder is another drug often used by steroid users. Unlike Letrozole Powder which is an aromatase inhibitor, Clomid is a selective estrogen receptor modulator (SERM). Both drugs are very effective but they work differently, so one can not be said to be better than the other.

If you want an aromatase inhibitor, Letrozole Powder is possibly the best at controlling estrogen symptoms while you’re on a steroid cycle while Clomid is a standard choice for PCT use. Letrozole Powder is effective at lowering overall estrogen so is excellent for both water retention control and gyno, while Clomid specifically targets the breast tissue.

For PCT usage, Clomid is considered a better choice because it does not suppress overall estrogen levels the way that Letrozole does which provides a better hormonal balance for restoring your normal testosterone production after a steroid cycle. By comparison, Letrozole Powder is generally considered too powerful as an estrogen reduction drug to be a good choice for PCT.

13. Buying Letrozole Powder to use as a pct supplement

Letrozole Powder can be bought online, in the same way as SARMs and generic Nolvadex/Clomid.

The problem is always the same though. You need to find an reliable supplier that sells these chemicals with purity guarantees.

AASraw supplies genius steroid raw powder and PCT supplements, you can get everything you need at the same time in one order. Buy Letrozole Powder bulk will get wholesale price.

14.References

[1] Lee VC, Gao J, Lee KF, et al. The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta. Hum Reprod. 2013 Nov;28(11):2912-9. PMID: 23980056.

[2] Tomao F, Spinelli G, Vici P, et al. Current role and safety profile of aromatase inhibitors in early breast cancer. Expert Rev Anticancer Ther. 2011 Aug;11(8):1253-63. PMID: 21916579.

[3] Yapura J, Mapletoft RJ, Pierson R, et al. A bovine model for examining the effects of an aromatase inhibitor on ovarian function in women. Fertil Steril. 2011 Aug;96(2):434-438.e3. PMID: 21696721.

[4] Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. Buzdar AU. Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S.

[5] Aromatase overexpression transgenic mice model: cell type specific expression and use of letrozole to abrogate mammary hyperplasia without affecting normal physiology. Mandava U, Kirma N, Tekmal RR. J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):27-34.

[6] “Dangers of Excess Estrogen In the Aging Male”. Faloon, William. Life Extension Magazine, November 2008.

[7] Aromatase inhibition, testosterone, and seizures. Harden C, MacLusky NJ. Epilepsy Behav. 2004 Apr;5(2):260-3.

[8] Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors. Boeddinghaus IM, Dowsett M. J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):85-91.

[9] Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats.

[10] Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. Buzdar AU. Clin Cancer Res. 2003 Jan;9(1 Pt 2):468S-72S.

15. How to buy Letrozole(Femara) Powder from AASraw?

❶To contact us by our email inquiry system,or leave your whatsapp number to us, our customer service representative(CSR) will contact with you in 12 hours.

❷To provide us your inquired quantity and address.

❸Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).

❹Payment done and the goods will be sent out in 12 hours.

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