Buy 2-Methoxyestradiol (362-07-2) hplc≥98% | AASraw
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2-Methoxyestradiol (362-07-2)

Rating: SKU: 362-07-2. Category:

AASraw is with synthesis and production ability from gram to mass order of 2-Methoxyestradiol (362-07-2), under CGMP regulation and trackable quality control system.

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Product Description


2-Methoxyestradiol (362-07-2) video




2-Methoxyestradiol (362-07-2) Specification:

Chemical Structure: Product Name: 2-Methoxyestradiol
Buy 2-Methoxyestradiol (362-07-2) hplc≥98% | AASraw Cas No.: 362-07-2
Molecular Formula: C19H26O3
Molecular Weight: 302.4
Synonyms: 2-Methoxyestradiol




2-Hydroxyestradol 2-methyl ether

Storage: Dry, dark
Documents(COA & HPLC etc.): Available

2-Methoxyestradiol (362-07-2) Description:

methoxyestradiol powder, also known as 2-ME, is an orally bioavailable estradiol metabolite with potential antineoplastic activity, hence it is an angiogenesis inhibitorIt also acts as a vasodilator.

2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis.



  • 1: Perez-Sepulveda A, España-Perrot PP, Norwitz ER, Illanes SE. Metabolic pathways involved in 2-methoxyestradiol synthesis and their role in preeclampsia. Reprod Sci. 2013 Sep;20(9):1020-9. doi: 10.1177/1933719113477483. Epub 2013 Mar 1. Review. PubMed PMID: 23456663; PubMed Central PMCID: PMC3745713.
  • 2: Machado-Linde F, Pelegrin P, Sanchez-Ferrer ML, Leon J, Cascales P, Parrilla JJ. 2-methoxyestradiol in the pathophysiology of endometriosis: focus on angiogenesis and therapeutic potential. Reprod Sci. 2012 Oct;19(10):1018-29. doi: 10.1177/1933719112446080. Epub 2012 Aug 8. Review. PubMed PMID: 22875846.
  • 3: Peyrat JF, Brion JD, Alami M. Synthetic 2-methoxyestradiol derivatives: structure-activity relationships. Curr Med Chem. 2012;19(24):4142-56. Review. PubMed PMID: 22709003.
  • 4: Verenich S, Gerk PM. Therapeutic promises of 2-methoxyestradiol and its drug disposition challenges. Mol Pharm. 2010 Dec 6;7(6):2030-9. doi: 10.1021/mp100190f. Epub 2010 Oct 21. Review. PubMed PMID: 20831190; PubMed Central PMCID: PMC3059899.
  • 5: Mueck AO, Seeger H. 2-Methoxyestradiol–biology and mechanism of action. Steroids. 2010 Oct;75(10):625-31. doi: 10.1016/j.steroids.2010.02.016. Epub 2010 Mar 7. Review. PubMed PMID: 20214913.