N-Boc-dolaproine(120205-50-7)

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AASraw is with synthesis and production ability from gram to mass order of N-Boc-dolaproine (CAS 120205-50-7), under CGMP regulation and trackable quality control system.

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Product Description

 

N-Boc-dolaproine(120205-50-7)video

 

 


 

I.N-Boc-dolaproine(120205-50-7)basic Characters:

 

Name: N-Boc-dolaproine
CAS: 120205-50-7
Molecular Formula: C14H25NO5
Molecular Weight: 287.352
Melt Point: 182 °C (dec.)
Storage Temp: 4°C, store under nitrogen
Color: White

 


 

II. N-Boc-dolaproine

(CAS 120205-50-7)

usage in steroids cycle

 

1. Names:

Product Name:(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)- 3-methoxy-2-methylpropanoic acid, (2R,3R)-BOC-dolaproine
Synonyms: ((2R,3R)-3-((S)-1-(tertbutoxycarbonyl)pyrrolidin-2-yl)-3-Methoxy-2-Methylpropanoic acid;Dolproline;N-Boc-dolaproline;(2R,3R)-BOC-dolaproine;N-Boc-dolaproine (CAS 120205-50-7); (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-Methoxy-2-Methylpropanoic acid (DAP);N-Boc-dolaproline acid;N-Boc-Dolaproline (K salt) (N-Boc-DAP-K salt) (free acid)

 

2. N-Boc-dolaproine (CAS 120205-50-7) Usage:

(2R,3R)-BOC-dolaproine is an β-methoxy-γ-amino acid component of dolastatin 10, an antineoplastic agent.

3. Warning on N-Boc-dolaproine
For research used only

4.Further instructions:
An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction
In this communication we report a stereoselective total synthesis of N-Boc-dolaproine (CAS 120205-50-7) (Dap), an amino acid residue of the antineoplastic pentapeptide Dolastatin 10. Our strategy is based on a Baylis–Hillman reaction between N-Boc-prolinal and methyl acrylate, followed by a diastereoselective double bond hydrogenation and hydrolysis of the ester function.

A simple and stereoselective approach for the total synthesis of N-Boc-dolaproine is described. The synthesis is based on the utilization of a Baylis–Hillman reaction and was accomplished in four steps with an overall yield of 27%.

 


 

III. N-Boc-dolaproine (CAS 120205-50-7) HCML

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IV. How to buy N-Boc-dolaproine from AASraw?

 

1.To contact us by our email inquiry system,or online skypecustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.

 


 

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