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Obeticholic Acid powder

Rating: SKU: 459789-99-2. Category:

AASraw is with synthesis and production ability from gram to mass order of Obeticholic Acid powder (459789-99-2), under CGMP regulation and trackable quality control system.

Obeticholic acid powder is used to treat PBC in adults and is sometimes used together with another drug called ursodeoxycholic acid (UDCA). Primary biliary cholangitis (PBC) is a chronic liver disease that gradually destroys bile ducts in the liver.

Product Description


Obeticholic Acid powder video




Obeticholic Acid powder basic Characters


Name: Obeticholic Acid powder
CAS: 459789-99-2
Molecular Formula: C26H44O4
Molecular Weight: 420.63
Melt Point: 108–110 °C
Storage Temp: Refrigerator
Color: White or off white Crystalline powder



Obeticholic Acid powder in Antineoplastic Agent usage



Generic Name: Obeticholic Acid powder (oh BET i KOE lik AS id)
Brand Name: Ocaliva


Obeticholic Acid powder Usage

This medication is used alone or in combination treatment for a certain liver disease (primary biliary cholangitis-PBC). This disease slowly destroys the bile ducts in the liver. When bile ducts are damaged, harmful substances can build up in bile andscar the liver. Obeticholic Acid powder works by causing your liver to make less bile, and by helping bile flow out of the liver. Obeticholic Acid powder may help slow worsening of primary biliary cholangitis and decrease symptoms such as tiredness, itchy skin, abdominal pain, and dry eyes and mouth.


What is the dosage of Obeticholic Acid powder

Usual Adult Dose for Biliary Cirrhosis

Initial dose: 5 mg orally once a day
Maintenance dose: 5 mg orally once a day; if adequate reduction in alkaline phosphatase (ALP) and/or total bilirubin is not achieved after 3 months, increase the dosage to 10 mg orally once a day
Maximum dose: 10 mg/day


Uses: For the treatment of primary biliary cholangitis:
-As monotherapy in adults unable to tolerate ursodeoxycholic acid (UDCA)
-In combination with UDCA in adults with an inadequate response to UDCA

Renal Dose Adjustments
No adjustment recommended.

Liver Dose Adjustments
Mild liver dysfunction (Child Pugh Class A): No adjustment recommended.
Moderate to severe liver dysfunction (Child Pugh Class B and C):
-Initial dose: 5 mg orally once a week
-Maintenance dose: 5 mg orally once a week; if adequate reduction in ALP and/or total bilirubin is not achieved after 3 months, increase the dosage to 5 mg 2 times a week (at least 3 days apart), and subsequently to 10 mg 2 times a week (at least 3 days apart) depending on response and tolerability
-Maximum dose: 10 mg/day

-Patients should be monitored for the occurrence of liver-related adverse reactions
-The potential risks should be weighed against benefits in patients with a history of clinically significant liver-related adverse reactions.

Dose Adjustments
Patients with intolerant pruritus:
-Add an antihistamine or bile acid binding resin
-Reduce the dosage to 5 mg every other day (patients intolerant to a daily dose of 5 mg) or 5 mg orally once a day (patients intolerant to a daily dose of 10 mg)
-Temporarily stop treatment for up to 2 weeks, then restart at a lower dose
-Consider discontinuation in patients with continued persistent, intolerable pruritus.


How Obeticholic Acid powder works

Obeticholic Acid powder is used alone or in combination with ursodiol (Actigall, Urso) to treat primary biliary cholangitis (PBC; a type of liver disease that destroys bile ducts, which allows bile to stay in the liver and cause damage) in people who cannot take ursodiol or in people who were not treated successfully with ursodiol alone. Obeticholic Acid powder is in a class of medications called farnesoid X receptor agonists. It works by decreasing the production of bile in the liver and increasing the removal of bile from the liver.



Before taking Obeticholic Acid powder, tell your doctor or pharmacist if you are allergic to it;or if you have any other allergies. This product may contain inactive ingredients which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bile duct blockage.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor beforebreast-feeding.


Obeticholic Acid Raw Powder

Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order can be sent out in 3 working days after payment.


Obeticholic Acid powder Marketing

To be provided in the coming future.


Does Obeticholic Acid powder Have Any Side Effects

Tiredness, mouth/throat pain, or fast/pounding heartbeat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many peopleusing this medication do not have serious side effects.

Although this medication is used to treat primary biliary cholangitis (PBC), it may also cause worsening of some liver symptoms. Tell your doctor right away if you have symptoms such as new or worsening skin itching, nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine, muscle/joint pain, swelling legs/feet/abdomen, or mental/mood changes. Your doctor may prescribe other medications such as bile acid-binding resins or antihistamines, or temporarily stop/adjust your dose of medication to help manage some side effects. Talk with your doctor about the risks and benefits of taking this medication.

A very serious allergic reaction to this drug is rare. However, get medical help rightaway if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.



How to buy Obeticholic Acid powder from AASraw


1.To contact us by our email inquiry system,or online skypecustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.