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Deflazacort Powder (14484-47-0)

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SKU: 14484-47-0. Category:

AASraw is with synthesis and production ability from gram to mass order of Deflazacort Powder (14484-47-0), under CGMP regulation and trackable quality control system.

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Product Description

 

Deflazacort Powder (14484-47-0) video

 

 


 

Deflazacort Powder (14484-47-0) Specification:

Chemical Structure: Product Name: Deflazacort
Cas No.: 14484-47-0
Molecular Formula: C25H31NO6
Molecular Weight: 441.51674
Standard: In-house
Storage: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Documents(COA & HPLC etc.): Available

Deflazacort Powder (14484-47-0) Description:

Deflazacort (trade name Emflaza among others) is a glucocorticoid used as an anti-inflammatory and immunosuppressant. Deflazacort is a prodrug. Its potency is around 70–90% that of prednisone.It belongs to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. Deflazacort is an inactive prodrug which is metabolized rapidly to the active drug 21-desacetyldeflazacort.It is used to treat a wide variety of conditions. Some examples include autoimmune diseases (for example, systemic lupus erythematosus (SLE), autoimmune hepatitis, sarcoidosis), joint and muscle diseases (for example, rheumatoid arthritis), and allergies and asthma.

 

Reference:

  • 1: McDonald CM, Sajeev G, Yao Z, McDonnell E, Elfring G, Souza M, Peltz SW, Darras BT, Shieh PB, Cox DA, Landry J, Signorovitch J; ACT DMD Study Group and the Tadalafil DMD Study Group. Deflazacort vs prednisone treatment for Duchenne muscular dystrophy: a meta-analysis of disease progression rates in recent multicenter clinical trials. Muscle Nerve. 2019 Oct 10. doi: 10.1002/mus.26736. [Epub ahead of print] PubMed PMID: 31599456.
  • 2: Kucukpolat S, Kocaaslan R, Kadihasanoglu M, Bagcioglu M, Kocan H, Sarica K. Is Medical Therapy for Distal Ureteral Stones Efficient? Tamsulosin versus Deflazacort: A Prospective Randomised Trial. Aktuelle Urol. 2019 Sep 19. doi: 10.1055/a-0770-2627. [Epub ahead of print] PubMed PMID: 31537025.
  • 3: Tantawy MA, Alweshahy S, Elshabasy DA, Youssef NF. Simultaneous Determination of Co-administrated Deflazacort, Aprepitant and Granisetron in Dosage Forms and Spiked Human Plasma by RP-HPLC/PAD. J Chromatogr Sci. 2019 Aug 28. pii: bmz062. doi: 10.1093/chromsci/bmz062. [Epub ahead of print] PubMed PMID: 31504281.

 

PRECAUTION AND DISCLAIMER:

This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.