Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) video
Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) basic Characters
|Name:||Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P)|
|Melt Point:||139 to 142 °C|
|Storage Temp:||Room Temperature|
|Color:||White or off white Crystalline powder|
Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) cycle
Brand Names: Pyridoxal-phosphate
Generic Name: PLP, pyridoxal-5′-phosphate or P5P
Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) Usage
Pyridoxal-5-Phosphate, or P5P as it is commonly known, is the active form of vitamin B6. In foods or most supplements, vitamin B6 is found in one of three forms: pyridoxine hydrochloride, pyridoxal, or pyridoxamine. Inside the body, these forms of B6 have to be converted by the liver to the active form the body needs – P5P. Low rates of conversion from the inactive to the active form of vitamin B6 have been reported, especially in people with impaired liver function, celiac’s disease, older adults, and in children with autism. By consuming vitamin B6 in the active P5P form, conversion is no longer necessary, and the full benefits are available immediately after absorption.
What is the dosage of Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P)
According to “Vitamin B6 Therapy: Nature’s Versatile Healer,” P5P may help relieve symptoms of seborrheic dermatitis, premenstrual syndrome, autism and certain types of anemia. The recommended dose of P5P varies based on the specific deficiency or medical condition you want to treat from 2.5 mg to 50 mg daily. You should, however, speak with a medical professional prior to taking any health supplement — including P5P.
How Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) works
In your body, P5P plays a fundamental role in amino acid metabolism, heme biosynthesis, neurotransmitter biosynthesis, collagen formation and glucocorticoid action. Additionally, P5P helps to balance your sodium and potassium levels by regulating the electrical functioning of your nerves, heart and musculoskeletal system. Alone and together with other enzymes, P5P helps your body to build and break down amino acids and to change amino acids from one to another. Further, P5P facilitates the release of stored energy from your liver and muscles and facilitates the production of antibodies and red blood cells.
Benefits of Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P)
P5P and Cardiovascular Risk
According to “Vitamin B6 Therapy: Nature’s Versatile Healer,” written by John Ellis, P5P has the capacity to lower your body’s levels of homocysteine. In your body, the amino acid homocysteine is not obtained from diet, but from another amino acid called “methionine.” Homocysteine is a potential risk factor for cardiovascular disease, and P5P can reduce methionine levels in your body, resulting in lower production of homocysteine. Additionally, P5P can help protect your body from coronary heart disease, hypertension and cerebral vascular disease.
P5P and Cancer
According to “Cecil Medicine: Expert Consult,” P5P deficiencies may contribute to pancreatic and cervical cancers. In many cases, women with cervical cancer present with a deficiency of vitamin B-6. Regarding pancreatic cancer, a study published in the “Journal of the National Cancer Institute” concluded that 26 percent of the pancreatic cancer cases studied may have been preventable with P5P supplementation prior to contracting the pancreatic cancer. Researchers have not published newer data involving these findings.
Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P)
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Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) Marketing
To be provided in the coming future.
Pyridoxal phosphate, (PLP, pyridoxal 5′-phosphate, P5P) overview
Everyone has heard of vitamin B6 and a few may even be able to tell you that the B vitamins have a lot of research on energy and the nervous system. Vitamin B6 is critical for life itself. Having low levels of this key nutrient can lead to skin disorders, depression, dizziness, headaches, and other, more serious problems, such as heart attacks and strokes. Yet you may be surprised to learn that vitamin B6 is one of the best natural compounds around to treat all kinds of nerve pain. But it is not always easy to get from the diet. Did you know that cooking, freezing, canning, storing or processing foods can deplete their vitamin B6 content by as much as 50%? And did you know that some people cannot use certain forms of vitamin B6 effectively? There is a special, active form of vitamin B6 that your body can easily utilize called pyridoxal-5-phosphate, or P5P for short. This form has amazing healing properties. I frequently recommend it to people suffering from nerve pain, burning feet (diabetic neuropathy), carpal tunnel syndrome, PMS, and edema (water retention), among other conditions. The results for these people have been outstanding. In this issue of Terry Talks Nutrition, we will review some of the conditions that can benefit the most from the active form – P5P – of vitamin B6, as well as a mineral partner that can greatly impact your health, or even prevent certain surgeries!
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