Estradiol hemihydrate (35380-71-3) video

Estradiol hemihydrate (35380-71-3) Specification:

Estradiol hemihydrate (35380-71-3) Description:

Estradiol Hemihydrate is the hemihydrate form of estradiol, the most potent, naturally produced estrogen. Estradiol hemihydrate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

Reference:

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• 2.Pgc1a is responsible for the sex differences in hepatic Cidec/Fsp27β mRNA expression in hepatic steatosis of mice fed a Western diet. Herrera-Marcos LV, Sancho-Knapik S, Gabás-Rivera C, Barranquero C, Gascón S, Romanos E, Martínez-Beamonte R, Navarro MA, Surra JC, Arnal C, García-de-Jalón JA, Rodríguez-Yoldi MJ, Tena-Sempere M, Sánchez-Ramos C, Monsalve M, Osada J. Am J Physiol Endocrinol Metab. 2019 Dec 17. doi: 10.1152/ajpendo.00199.2019. [Epub ahead of print] PMID: 31846369
• 3.Acute ovarian hormone treatment in freely cycling female rats regulates distinct aspects of heroin seeking. Vazquez M, Frazier JH, Reichel CM, Peters J. Learn Mem. 2019 Dec 16;27(1):6-11. doi: 10.1101/lm.050187.119. Print 2020 Jan. PMID: 31843977