SR9011 powder video
I.Raw SR9011 powder basic Characters:
|Storage Temp:||4°C for 1 year|
|Color:||white to light yellow Powder|
II. Raw SR9011 powder in bodybuilding usage
2.Raw SR9011 powder Usage
The optimal dosages range from 20 to 30 milligrams (mgs) per day. However, there is one drawback – due to a very short half life, you will need to space it out throughout the day for the best balance of the active substance in the body.
Thus, it is best to use stenabolic every 2-4 hours, depending on the exact dosage used. For example, when the daily dosage is 30 mgs, you can take 10 mgs every 4 hours.
SR9009 and SR9011 powder are attractive as performance-enhancing substances due to their REV-ERB agonist effects and thus circadian rhythm modulation activity. Although no pharmaceutical preparations are available yet, illicit use of SR9009 and SR9011 powder for doping purposes can be anticipated, especially since SR9009 is marketed in illicit products. Therefore, the aim was to identify potential diagnostic metabolites via in vitro metabolic studies to ensure effective (doping) control. The presence of SR9009 could be demonstrated in a black market product purchased over the Internet. Via human liver microsomal metabolic assays, eight metabolites were detected for SR9009 and fourteen metabolites for SR9011 powder by liquid chromatography–high resolution mass spectrometry (LC–HRMS). Structure elucidation was performed for all metabolites by LC–HRMS product ion scans in both positive and negative ionization mode. Retrospective data analysis was applied to 1511 doping control samples previously analyzed by a full-scan LC–HRMS screening method to verify the presence of SR9009, SR9011 powder and their metabolites. So far, the presence of neither the parent compound nor the metabolites could be detected in routine urine samples. However, to further discourage use of these potentially harmful compounds, incorporation of SR9009 and SR9011 powder into screening methods is highly recommended.
SR9011 powder is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 powder alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.
The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 powder decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
A new compound called SR9011 powder increases metabolism, fat burning, and muscle growth in the lab.Scientists at The Scripps Research Institute (TSRI) have successfully tested a drug, called SR9011 powder,in mice that kickstarts metabolism and results in increased muscle development.Essentially, it’s an exercise regime in a pill.
SR9011 powder alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism.
Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance.
3.Warning on SR9011 powder
SR9009 also reduced the growth of glioblastoma, a form of brain cancer, and lengthened survival time in mice with glioblastoma tumors. It worked about as effectively as temozolomide, the current standard treatment for glioblastoma, but it did so without any apparent side effects. Temozolomide often causes hair loss, gastrointestinal upset, and nervous system problems, among other effects. SR9009 and SR9011 powder both pass the blood-brain barrier, enabling them to reach the brain, but they are not orally available, so researchers had to inject them into the animals.
The data suggest that circadian clock-targeted agents could treat a wide range of cancers with few side effects, the researchers say. But they point out that further safety testing and trials in people are necessary.
The Salk team found that the two compounds kill cancer cells by inhibiting lipid production and “autophagy,” a process in which cells degrade unwanted cellular components. Cancer cells need both metabolic processes to grow and reproduce.
SR9011 powder VS SR9009 powder
The difference between SR9009 and other diet pills is in its chemistry. SR9011 powder is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it’s stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 powder ensures that food and excess fat are used as energy.
5.SR9011 Raw Powder:
Min order 10grams.
The inquiry on normal quantity(Within 1kg) can be sent out in 12 hours after payment.
For larger order(Within 1kg)can be sent out in 3 workingdays after payment.
6. SR9011 Raw Powder Recipes:
To inquiry our Customer Representitive(CSR) for details, for your reference.
7. Raw SR9011 powder Marketing:
To be provided in the coming future.
III. Raw SR9011 powder HNMR
IV. How to buy SR9011 powder from AASraw?
1.To contact us by our email inquiry system,or online skypecustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.
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