Trastuzumab

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AASraw is with synthesis and production ability from gram to mass order of Trastuzumab (CAS 180288-69-1), under CGMP regulation and trackable quality control system.

Trastuzumab powder is used in the treatment of HER2-positive breast cancer. HER2 protein overexpression is observed in 25%-30% of primary breast cancers.Trastuzumab has been shown, in both in vitro assays and in animals, to inhibit the proliferation of human tumorcells that overexpress HER2. It is a mediator of antibody dependent cellular cytotoxicity, in that the binding of the antibody to HER2 overexpressing cells leads to preferential cell death.

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Product Description

 

Trastuzumab video

 

 


 

I.Trastuzumab basic Characters:

 

Name: Trastuzumab
CAS: 180288-69-1
Molecular Formula: C10H14N6O5
Molecular Weight: 298.25536
Melt Point: 61-71 °C
Storage Temp: 2-8 °C
Color: White powder

 


 

II. Trastuzumab (180288-69-1) usage in steroids cycle

 

1. Names:

Trastuzumab (CAS 180288-69-1), trade name is Herceptin.

 

2. Trastuzumab Usage:

Trastuzumab is given through an infusion into vein (intravenous, IV). The first dose is given over 90 minutes. If well-tolerated subsequent maintenance doses may be given over 30 minutes.
The amount of Trastuzumab (180288-69-1) that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.

 

3. Warning on Trastuzumab

A serious but uncommon side effect of Trastuzumab can be interference with the pumping action of the heart. The incidence of heart problems (heart failure) increase in people with heart disease or other risk factors such as radiation to the chest, advancing age, and use of other heart-toxic drugs (such as doxorubicin and cyclophosphamide). Your doctor may check your heart function before you may take any Trastuzumab and will monitor your heart closely during your treatment. Trastuzumab (180288-69-1) may be discontinued if symptoms of heart failure appear.

 

4.Further instructions:

Monoclonal antibodies are a relatively new type of “targeted” cancer therapy. Antibodies are part of the immune system. Normally, the body creates antibodies in response to an antigen (such as a protein in a germ) entering the body. The antibodies attach to the antigen in order to mark it for destruction by the body’s immune system. In the laboratory, scientists analyze specific antigens on the surface of cancer cells (target) to determine a protein to match the antigen. Then, using animal and human proteins, scientists work to create a special antibody that will attach to the target antigen. Antibodies will attach to matching antigens like a key fits a lock. This technology allows treatment to target specific cells, causing less toxicity to healthy cells. Monoclonal antibody therapy can be done only for cancers in which antigens (and the respective antibodies) have been identified.

Trastuzumab works by targeting the HER2/neu receptor on cancer cells. The HER2 gene produces a protein receptor on the cell surface that signals normal cell growth by telling the cell to divide and multiply. Some cancerous breast tissue has too much HER2 (HER2/neu overexpression), triggering the cells to divide and multiply very rapidly. Trastuzumab (180288-69-1) attaches to the HER2 receptors to prevent cells from multiplying, preventing further cancer growth and slowing cancer progression. It may also work by stimulating an immune mechanism.

 


 

III. Trastuzumab (180288-69-1) HCML

We are Aprepitant powder supplie,Aprepitant powder for sale,Raw Aprepitant powder (170729-80-3) hplc≥98% | AASraw R&D Reagents

 


 

IV. How to buy Trastuzumab from AASraw?

 

1.To contact us by our email inquiry system,or online skypecustomer service representative(CSR).
2.To provide us your inquired quantity and address.
3.Our CSR will provide you the quotation, payment term, tracking number, delivery ways and estimated arrival date(ETA).
4.Payment done and the goods will be sent out in 12 hours(For order within 10kg).
5.Goods received and give comments.

 


 

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