Most competitive bodybuilders always go an extra mile looking for drugs to boost the leanness of their bodies. One of the most powerful drugs used by weightlifters is called DNP. The weightlifters refer to this drug as the most powerful fat burner on earth. This is because it provides amazingly powerful results in fat burning. Some of the most important things you need to know about this product include knowing what the product entails, how it works, the benefits, its results, half-life, side effects, its dosage and where to buy it, as explained in this article.
What is 2,4-Dinitrophenol(DNP)?
2,4-Dinitrophenol (DNP) is one of the drugs that has gained a lot of attention among the bodybuilding communities, fitness and the general public for its amazing weight loss effects. This product is an organic compound with the ability to alter the process of cellular respiration in the body. Initially, the product was used for a wide range of industrial functions including being used as a photographic developer, pesticide, dye and wood preservative.
The discovery of its weight loss effects of DNP was made in the year 1933 by Maurice Tainter, a researcher from Stanford University. It is during this period that many people used the drug as a dieting aid. People could lose up to 3.3 pounds in one week without necessarily following any dietary restrictions. This made the drug become one of the treatments for obesity, which was used to treat a good number of patients.
However, it was also discovered that the product was associated with adverse side effects and the physicians warned the users of these effects. These effects would range from one individual to another. For instance, some people would tolerate a standard dose while others would be affected by even the smallest doses. In some extreme cases, there were reported several dinitrophenol deaths. As a result, the drug was banned in the US’s Food and Drug Administration (FDA) in 1938. The drug was since then produced as an underground drug until 1980’s when it returned in the market as a weight loss drug. During this period, it was widely sold online and was being referred to as the ‘king of weight loss drugs’. However, being sold online created many chances of misuse and lack of proper directions from experts.
2,4-Dinitrophenol (DNP) powder has a molecular formula of C6H4N2O5 and a molecular weight of 184.107g/mol. It is also known by other names including Dinitrophenol Dimitrios, Dinitrenal, Nitromet and Alpha. The drug is chemically synthesized in two forms, 2,4-Dinitrophenol and sodium dinitrophenolate. 2,4-Dinitrophenol (DNP) powder is with yellow color.
How does 2,4-Dinitrophenol(DNP) help in weight loss?
When thinking about the weight loss effect caused by DNP, one of the questions that one may ask is, how does DNP cause weight loss? Here is an explanation of the action mechanism of DNP that results in weight loss when you take 2,4-dinitrophenol(DNP):
Under normal cases, cells consume glucose in presence of oxygen. This takes place within mitochondria of the body cells in a process referred to as the Krebs cycle. As a result of this process, protons diffuse into the matrix of the mitochondria via the inner membrane of the mitochondria producing a chemiosmotic gradient. This gradient is then relieved when these protons drift back through inner membranes of the mitochondria.
These protons can only re-enter through the adenosine triphosphate (ATP) synthase enzyme. Passing of the protons through this enzyme leads to the creation of ATP, which is the source of energy for the cells. This process, therefore, ensures a sustainable supply of energy in the body cells.
When Dinitrophenol is added, it prevents the drifting back of the protons into the mitochondrial inner membranes. This leads to an increased concentration of protons between the membranes of the mitochondria. This concentration exceeds the concentration in the matrix of mitochondria, which leads to combating of the action of the enzyme ATP synthase. As a result, the energy is not used for the production of ATP neither is it stored in the body. This energy is rather released as waste in form of heat.
To cover the shortage of ATP caused by the DNP, the body will be forced to burn more carbohydrates, proteins and fats. This increases the rate at which fat, proteins and carbs are burnt in the body. This causes a rapid fat and weight loss.
This also leads to the alteration of the rate of metabolism rates, increasing it to higher rates. With the increased rate of metabolism, the body burns the fats and carbohydrates faster.
DNP also reduces the efficiency of the metabolic processes. This is done by increasing the production of heat in body cells, a process known as uncoupling. As a result, the body breaks down more of the fats and carbohydrates than usual. This may cause the metabolism rate to rise by as high as 50 per cent. The individuals under the DNP dosage will, therefore, experience a great deal of weight loss. The individuals do not need to have any dietary control when using DNP for weight loss.
2,4-Dinitrophenol(DNP) benefits in bodybuilding
The bodybuilders have also known to use DNP as a supplement in their bodybuilding training. The primary reason DNP bodybuilding function is helping in excessive fat and weight loss. DNP has many advantages that contribute to the weight loss for the bodybuilding individuals. The following are some of these advantages.
- The DNP stimulates the disassociation of the oxidative phosphorylation thus increasing the rate of metabolism.
This affects the amount of ATP produced in the cells in that when exposed to the DNP, the cells produce a reduced amount of ATP as compared to the normal production. To meet the energy demands needed for the increased metabolism, the body is put under pressure to produce more ATP.
- DNP contributes to increased production of heat by the body.
For the body to produce less ATP, there is an alteration of protons’ electrochemical gradient. This means that the energy that could be used for the synthesis of ATP is disposed of as heat. When the body produces excess internal heat, a lot of calories are consumed resulting in weight loss.
- DNP weight loss is also stimulated by the increased cellular stimuli in glucose breakdown (glycolysis).
When the processes of inhibition of uncoupling and increased glycolysis are combined, a lot of carbohydrates are consumed. These processes result in a decreased efficiency in energy production, which eventually lead to the loss of weight.
- DNP may be used to provide a remedy to some of the neurological disorders associated with ageing.
Though this has not yet been put into practice by human beings, researches have shown that DNP is potentially a significant compound for this purpose. For instance, research has shown that the drug can be used for treating people who have just suffered from a stroke. This is because it has the potential to counter the damages caused by the stroke. The drug also has the potential to counter the oxidative stress in patients suffering from Huntington’s disease. This is enabled by the enhanced motor function caused by DNP.
- DNP steroid can also be used medically for treatment of Parkinson’s disease patients.
Just as it functions for Huntington’s disease, DNP helps in enhancement of motor function and reduce the chances for damages. These functions have however not been applied for human beings for the need for further research.
- People under dieting may use DNP supplement as an aid for their programs.
This is because it does not require any regulations on how you eat. You can actually eat a lot and still achieve your goals in weight loss. This drug may also act as an appetite suppressant.
- DNP can also be applied medically as a treatment for liver disease.
This condition may lead to other dangerous diseases such as cancer. Research has however shown some promising abilities of DNP to combat this disease in rats.
- DNP has the potential to treat patients suffering from diabetes.
Diabetes is enhanced by insulin resistance. With insulin resistance, the normal response of the cells to the sugar controlling hormone is altered. This causes imbalances in the sugar levels in the cells. DNP has the ability to improve the sensitivity to insulin in the cells. This helps to reduce the chances of diabetes development.
- DNP is a great remedy for people seeking to shed body fat within a very short time.
This can be an absolute solution for someone who is, for instance, looking to have a great shape for a show. This is because when your body is under DNP, it will be forced to use the stored fat to produce energy in order to cover the energy deficit created by DNP. In addition, not much of the food you take will be used for storage of fat. You, therefore, lose more fat when your body requires more energy than normal. Many bodybuilders have reported successful testimonials after using the DNP fat burner.
- Due to Dinitrophenol weight loss effects and ability to burn fat, it may be used to treat people with obesity-related conditions.
The advantage about this is that it does not damage other organs or their functions if it is used properly. The increased metabolic rate causes great consumption of calories thus causing weight loss. This functions the same way with the thyroid drugs.
2,4-Dinitrophenol before and after
DNP can be thought as one of the most effective compounds used for weight loss and bodybuilding. This, however, requires the users to be well informed and keen in order to reduce the chances of dangers caused by DNP side effects. DNP bodybuilding and DNP weight loss results can be seen within very short times it has been the case with many users. For instance, some of the users have reported having lost up to 6kgs within ten days without any specific diet or exercise. This was accompanied by up to 20% loss on body fat.
While looking for DNP before and after results, it is important to note that it does not work the same way for all people. To some people, the product will help under normal doses while it may have adverse reactions to other people even with the lowest DNP doses.
With proper DNP dosage, you can have very impressive DNP drug before and after results. In most cases, the bodybuilders lose between 5 and 15pounds. The advantage is that DNP weight loss is not accompanied by negative feedback from the other organs. Though there may be some water retention, this water is shed off after discontinuing the dose. As a result, the weight loss during the DNP cycle may be masked by water retention, making it difficult to calculate the exact weight loss while on the cycle. During the post DNP cycle, the retained water is shed off and one can count the exact weight lost during on the DNP steroid. While on the cycle, it is important to keep taking water because the increased heat production gives you a constant feeling of thirst and sweating. Some people prefer taking the cycle during the holidays and winter months since the sweating may be a little annoying and discomforting.
DNP also causes higher demand for glucose in the body through uncoupling of ATP, which forces the body to upregulate transporting of glucose. This plays a significant role in weight loss effect.
Some people do stack DNP with insulin to improve the DNP weight loss results. Insulin increases drastically the uptake of glucose creating an anabolic environment for weight loss
People with obesity signs may also realize some significant changes in their condition under the DNP weight loss schedule. Under standard therapeutic doses, the body metabolism rate may rise up to a double the normal with minimal or no toxic signs. This causes rapid fat burning effect thus reducing obesity.
Apart from fat and weight loss, DNP is also associated with other benefits including reduction of T3. This is particularly if you are under an androgenic anabolic cycle. T3 is responsible for the catabolic muscle loss which may happen after the DNP cycle. At some point, the DNP may reduce the T3 levels to very low or below the optimum levels. In such cases, you may need to stack some small doses of T3 in your cycle
DNP also gives your body an anabolic rebound which improves your look into a more lean and anabolic figure. The drug also enhances the immune system.
2,4-Dinitrophenol half life
When dealing with drugs such as steroids, the half-life information is very crucial. A half-life of a drug is the period taken for the body to eliminate half of the drug from the system. For instance, if you take 100mg of a drug with a half-life of one hour, it means that your system will have 50mg of the drug after one hour. The drug will, therefore, take 2 hours to be completely eliminated from the system.
DNP steroid has a long half-life lasting for up to 36 hours. The DNP half life means that if someone takes a dose of 100mg, the body will still have 50mg 36 hours after the dosage and 25mg after another 36 hours. For the drug to be completely eliminated, it may take up to 252 hours.
The knowledge about the DNP half life information helps you in timing your dosages. This is because it takes a long time with the body having the drug. As a result, it may be recommendable to take low doses with long cycles. For instance, one could take a 25 days cycle of DNP fat burner pills at a dose of 40mg per day.
It is important to note that due to the long half-life, the amount of the drug in the blood continues to increase every time you take a new dose. These concentrations may rise to unexpected levels. This is the reason why the knowledge about the DNP half life is an important thing to know before taking a DNP bodybuilding cycle. It helps you to time the dosage appropriately to avoid uncontrolled concentrations of DNP in the body.
When it comes to DNP dosage, one is supposed to be very careful and follow keenly the recommended dosage. This is because it may be fatal to take DNP in an uncontrolled dosage. Some of the DNP deaths reported were as a result of overdosing the drug. Though it has not been known what exact dose leads to death, estimates have been made that a dosage that exceeds 2500mg may be fatal. As stated earlier, taking small dosages with long cycles could be one of the safest ways to dose DNP. With DNP half life being so long, it means that the drug takes a long time to clear from the system. You should therefore not just assume that you can handle more than the recommended dose. During the DNP dosage, it is also important to avoid alcohol. DNP exhibits its results in varied ways depending on an individual. You must not feel it know that it is working.
Depending on the tolerance to the drug, individuals may decide to take low doses with long cycles or high doses with short cycles. For instance, a low dose with a long cycle may look like this:
|1||200mg per day|
|2||200mg per day|
|3||200mg per day|
|4||200mg per day|
|5||200mg per day|
|6||200mg per day|
|7||200mg per day|
|8||200mg per day|
|9||200mg per day|
|10||200mg per day|
|11||200mg per day|
|12||200mg per day|
|13||200mg per day|
|14||200mg per day|
|15||200mg per day|
|16||200mg per day|
|17||200mg per day|
|18||200mg per day|
|19||200mg per day|
|20||200mg per day|
|21||200mg per day|
In this kind of dosage, you should be taking the drug in two parts for every day. That is, 100mg in the morning and 100mg in the evening. You should first run the cycle for the first fourteen (14) days to determine if you have allergies or toxic results. For veteran users, one may continue for the three weeks (21 days).
For a short cycle with high dosage, the cycle may look like this:
|1||200mg per day|
|2||200mg per day|
|3||200mg per day|
|4||200mg per day|
|5||400mg per day|
|6||400mg per day|
|7||400mg per day|
|8||400mg per day|
|9||400mg per day|
|10||400mg per day|
|11||400mg per day|
The dosage for such a cycle should be started with a small dose of 200mg per day (divided as 100mg in the morning and 100mg in the evening), in the first days. However, veteran users may decide to neither increase the dosage or the number of days in the cycle.
DNP side effects
While DNP weight loss pills remain the most effective agent for weight loss, it is also associated with some side effects. Some of the extreme DNP side effects may be very dangerous and lead to serious risks to human life. However, there are safer ways to take DNP weight loss pills to minimize these side effects. The following are some of the side effects associated with 2,4-dinitrophenol(DNP):
All the users of DNP experience an excessive heat production in their bodies. The body temperature rises above the normal giving the user a very uncomfortable state.
Since DNP causes depletion of the ATP, the body is left without energy. This increases the feeling of lethargy and you feel weak to carry out any simple task. Though the extent of this effect depends on the amount of the DNP chemical you take in the body, some people may have extreme lethargy to a point of being bedridden. This is because they may be unable to even eat. At this point, one should not continue with the dose. Lethargy may be accompanied with other problems such as a headache.
- Water retention
Water retention effect of DNP occurs as a result of overproduction of heat in the body. Heat production leads to vasodilation which in turn causes the expansion of the blood vessels. The expansion of blood vessels increases the volume of blood flow. This also causes the retention of water. The expansion of the blood vessels also reduces the blood pressure. The body stores more calcium as a result, which causes more water retention. This water causes muscle bloating. In extreme cases, it may cause depletion of potassium since the diuretics do not offer sufficient disposal of reined water. This may put the user at a death risk.
Dehydration is one of the most serious DNP side effects. People under DNP dosage experience constant shortage of water in the body. The users are therefore advised to take plenty of water while on the dose. This is because very low levels of water in the body may put the body vulnerable for overheating which can lead to death.
A good percentage of DNP users experience nausea as one of the side effects of DNP fat burner pills. This could be resulted by many things including electrolyte imbalances, low pH in the blood, and dehydration among other causes.
- Depletion of electrolyte
Since DNP is associated with excessive sweating, a lot of water and salts are lost through sweating. Taking plenty of water may not be fully helpful since it only replaces water but not the salts. Users may, therefore, use v8 juice as a remedy for this.
Diarrhoea may be as a result of the lost salts in the body. The undissolved DNP causes osmotic imbalances upon reaching the large intestines. This is another reason why DNP users may experience cases of diarrhoea.
Though the cases of allergies are rare, they still manifest in some individuals. Some people may experience phantom itches in some parts of the body such as around the torso. The itches may eventually turn into rashes around the face, lips among other parts. People experiencing allergies may buy ant-allergies drugs to combat the effect. Most of the DNP chemical allergies are however tolerable unless in extreme cases where one should stop the cycle.
- Yellow vision
In very rare cases, some individuals under DNP medication may see yellow spots when they look at a white surface. However, this side effect does not have further effects and does not continue after you discontinue DNP.
Other DNP side effects may include the following:
- Irregular heartbeats
- Flushed skin
- Rapid breathing.
- Foul taste and dryness in mouth after taking the pills.
- Lack of sleep
Is it safe to take DNP
Though DNP has been marked as illegal for human consumption, it remains to be the most potent drug existing for weight loss. No other drug can be compared to it when it comes to the weight loss effects. However, if not properly used, this could be the most dangerous drug that can even lead to death. Almost all the DNP users experience high levels of heat production in their bodies. This leads to excessive sweating. As stated earlier, this drug does not have any negative impacts on some important body organs such as the liver, kidneys.
For you to improve your safety and comfort when on DNP dose or cycle, here are some tips about how to avoid DNP side effects you should always follow:
- Diet-You should never take DNP if your stomach is empty. Some of the suggested foods to include in your diet while on DNP include blueberry yoghurt. This acts as an antioxidant due to blueberries while yoghourt helps in digestion. Also, take foods with high fibre.
- Low initial dosages– Always start your cycle with a small dose, for example, 200mg per day for the first days of your cycle. Even when you do not feel anything, it is important to note that it is there in the body since it has a long DNP half Your first four days on low DNP dose will enable you to test how tolerable you are to the drug.
- Include other supplements while taking DNP. Supplements such as ECA may be helpful to maintain high energy and enhance fat loss. It may also be necessary to use antioxidants such as Alpha Lipoic Acid (aids management of fat and blood sugar), grape seed extract, fruits, green tea, trimethylglycine and vitamins C and E.
- Ensure you are taking enough water during the DNP cycle.This is because DNP induces thirst mostly due to excessive sweating.
- It is recommended to take the drug during the winter to combat the excessive sweating.
- If you are having workouts during the DNP cycle, ensure that you keep the workouts low, especially if you are taking a dosage of 400mg and above.
- Always do research to know the interactions between DNP and other drugs. This will help you to manage your cycle in case you are on medication with other drugs.
For you are safe on DNP, you must know how to properly dose the drug. You should also never overdose or exceed the dosage to 1gram. Such dosage is very fatal. You must as well weigh between the benefits you get from the drug and the risks you are exposing yourself to.
Where to buy DNP
When it comes buying DNP fat burner pills, it is important to note that the drug has been marked illegal in some countries. However, it is not illegal to sell the drug for industrial purposes and it is sold by some companies under CAS number DNP （51-28-5）.
While the availability of DNP might be limited in some places, it is easy to access DNP weight loss powder since they are available in the online shops. There exist websites that sell this product to the users online. A very good example of these websites where you can get DNP weight loss powder for sale is AASraw.
The accessibility of DNP powder online is very simple since it takes less time to find the websites that sell the drug. Considering the potency and the dangers associated with DNP fat loss, one needs to be very careful when purchasing this product online. This is because buy DNP powder online may be associated with fraud and you might end up buying the fake DNP.
The users must also understand the synonyms used by the sellers when dealing with DNP for sale. The advantage of buying DNP powder online is that it provides the users with a very convenient source of the drug. Some of the online sellers will provide customer or user reviews. These reviews may be very useful for your research, as they will help you know how other users are feeling about the product or the sellers themselves. With this kind of information, you will understand the experiences of the other users of DNP powder for sale. With such insight, you can make an informed decision when you want to buy DNP powder online.
DNP remains to be the most potent product used for weight loss purposes by different people, including the bodybuilders. Though this product is associated with some dangers and life risks, when used properly, it provides amazingly impressive results. The product has a well-elaborated mechanism in which it causes weight loss. DNP is also used for other clinical purposes such as treating obesity and diabetes.
When seeking to use DNP fat burner pills, it is important to; pay attention to various details about the drug. These include the dosage and proper timing of the DNP dosage using the DNP half life knowledge. Another important factor to consider is the side effects associated with this drug. One should as well consider their diet during the dosage as well the DNP supplements to combat the side effects. Always get advice from the experts and in combination with the information about DNP, you can be safe on the DNP weight loss drug.
1. Bagchi Debasis, Preuss Harry G.; Obesity: Epidemiology, Pathophysiology, and Prevention (2007). P.200, p.201, p.212, p.561
2. Henn Debra, deeugenio Deborah, Triggle D. J.; Diet Pills (2005) p.42
3. Versaw Pam Grace; Effect of the Uncoupler 2,4-dinitrophenol on Submitochondrial Particles (1975) p.9, p.
4. Ledford (Jr.)Roy Merl; The Effect of 2, 4-dinitrophenol Upon Frog Heart Metabolism and Function (1949) p.23, p.25, p.26.
5. Breguet Amy E.; Diet Pills (2008) p.21, p. 90.
6. Blachford Stacey, Krapp Kristine M.; Drugs and Controlled Substances: Information for Students(2003) p.130
7. Jameson J. Larry, De Groot Leslie J.; Endocrinology: Adult and Pediatric E-Book (2005) p. 1397